Benzoyl hydrazine derivative P and synthesis and application thereof

Abstract

The invention relates to detection of a fluorescence method on metal ions, and particularly relates to a benzoyl hydrazine derivative P which identifies and detects two different metal ions Mg<2+> andAl<3+> separately in different pH conditions. The structural formula of the benzoyl hydrazine derivative P is as shown in a formula (1). The preparation method of the benzoyl hydrazine derivative P comprises the following steps: firstly, carrying out hydrazinolysis on ethyl salicylate; carrying out a reaction with o-hydroxy naphthaldehyde at a molar ratio of 1 to 1 for 4 hours at 80 DEG C in anhydrous ethanol; cooling the mixture and separating out a solid and carrying out suction filtration; washing the mixture with a lot of water and anhydrous ethanol successively; and drying the solid to obtain a light yellow solid pure product P. The benzoyl hydrazine derivative P can be used for detecting Mg<2+> and Al<3+> separately in different pH conditions as a fluorescent probe. The benzoyl hydrazine derivative P is obtained by means of an effective synthetic means and shows relatively good selectivity on the metal ions Mg<2+> and Al<3+> separately. On a basis of an optimized experimental condition, the metal ions Mg<2+> and Al<3+> can be detected separately. The formula is as show in the description.

Description

technical field [0001] The invention relates to the detection of fluorescent probes, in particular to a benzohydrazide derivative P and its synthesis and application. Background technique [0002] Among the reported fluorescent molecular probes, most of them are a kind of probe to realize the detection of specific target substances. [1-3] . It has also been reported that the same probe uses different mechanisms to detect different metal ions [4] . However, it is rare to report that the same probe can detect different metal ions under different pH conditions. [0003] Benzohydrazide derivatives have excellent optical properties and are easy to synthesize, and have been widely used in metal ion fluorescent probes. Fluorescent probes based on benzoyl hydrazide derivatives have been applied to the detection of mercury ions, lead ions, iron ions, chromium ions, and copper ions, but they are rarely used in the detection of aluminum ions and magnesium ions. It has not been rep...

AI Technical Summary

Problems solved by technology

Fluorescent probes based on benzoyl hydrazide derivatives have been applied to the detection of mercury ions, lead ions, iron ions, chromium ions, and copper ions, but they are rarely used in the detection of aluminum ions and magnesium ions. It has not been reported that the needle can simultaneously realize the detection of the two ions under different pH conditions

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