24 results about "Hydrazine derivatives" patented technology

Disclosed in the present application are a perovskite thin film layer (4) and a preparation method therefor, and a perovskite silicon stacked solar cell and a preparation method therefor. The perovskite thin film layer (4) comprises a perovskite buried modification layer (41) stacked on the surface of a nickel oxide hole transport layer (3) in the perovskite solar cell as well as a perovskite light absorption layer (42) stacked on the surface of the perovskite buried modification layer (41), wherein the perovskite buried modification layer (41) is doped with hydrazine and / or hydrazine derivatives.

The invention relates to the technical field of naphthalimide preparation, in particular to a synthetic method of naphthalimide derivatives. Comprising the following steps: dissolving a mixture of 1, 8-naphthalic anhydride and 4-aminoacetophenone in acetic acid containing sodium acetate, carrying out a reflux reaction, after the reaction is completed, cooling the mixture to room temperature, filtering to obtain a crude product, and washing to obtain a pure compound 1; the method comprises the following steps: dissolving a mixture of a compound 1, a hydrazine derivative and an acid catalyst in an organic solvent, carrying out a reflux reaction, after the reaction is completed, cooling the mixture to room temperature, filtering to obtain a crude product, and washing to obtain the naphthalimide compound. The synthesis reaction is safe and reliable, the process is simple and easy to control, and the reaction yield is high; the combination of the synthesized drug and DNA has spontaneity, and the drug has good anti-proliferative activity.

The invention provides a polymer fluorescent nano-film, a template-free self-assembly preparation method thereof and application of a nerve poison sensing detection agent, and the polymer fluorescent nano-film is prepared on a gas-liquid interface through dynamic acylhydrazone bond condensation reaction by taking a column [5] arene hydrazide derivative and tetraformyl tetraphenylethylene as film building monomers. The polymer fluorescent nano-film is prepared through template-free self-assembly, the preparation process is simple, the conditions are mild, and the accurate regulation and control of the film thickness can be realized by changing the concentration of the precursor solution or the volume of the solution per unit area. The prepared film has a flat, smooth and defect-free surface, has excellent mechanical properties, shows good toughness and puncture resistance, shows excellent sensing performance on a nerve toxic agent simulant diethyl chlorophosphate, has excellent detection capability on a real nerve toxic agent sarin under the assistance of a solvent, and can be widely applied to the field of neurology and neurology, such as neurology, neurology, neurology, neurology, neurology, neurology, neurology, neurology, neurology, neurology, neurology and neurology. The method is expected to play an important role in the fields of public place safety monitoring and the like, and has a wide application prospect.

A method of forming high quality a-BN layers. The method includes use of a precursor chemistry that is particularly suited for use in a cyclical deposition process such as in chemical vapor deposition (CVD), atomic layer deposition (ALD), and the like. In brief, new methods are described of forming boron nitride (BN) layers from precursors capable of growing amorphous BN (a-BN) films by CVD, ALD, or the like. In some cases, the precursor is or includes a borane adduct of hydrazine or a hydrazine derivative.

The invention discloses a preparation method and application of a coumarin-hydrazide-based semi-sandwich type iridium and ruthenium complex, the structural formula of the complex is as shown in formula (I), the complex takes a coumarin-hydrazide derivative as an NO bidentate ligand, and an oxygen coordination atom in the ligand is derived from hydroxyl of a coumarin mother nucleus; iridium or ruthenium is used as a metal center, benzene is used as a unique solvent, alkali does not need to be added additionally under the protection of nitrogen, and the ligand can be prepared through a coordination reaction of the ligand and a metal dimer. The complex shows good anti-cancer activity, the drug effect of the complex is close to that of cis-platinum, and the complex has the potential value of becoming a novel anti-cancer drug.

The benzyl hydrazine derivative has the advantages of being good in activity and novel in structure, the benzyl hydrazine derivative serves as an RIPK1 small-molecule inhibitor, necroptosis induced by TNF-alpha can be reduced, and therefore the anti-inflammatory effect is achieved, and the benzyl hydrazine derivative can be used for preparing drugs for treating inflammation-related diseases such as diabetic nephropathy.

Provided is a production method comprising step A of reacting a compound represented by Formula (2):wherein R1, R2, and R3 are the same or different, R1 represents —COR, R2 and R3 each represent a hydrogen atom or —COR, and R4 represents a C1-C12 alkyl group or a C6-C12 aryl group; with a fluorinating agent containing IF5, an amine, and HF at 80° C. or lower throughout the reaction from the start to the end. This production method is capable of synthesizing a compound (N-fluoroalkylated hydrazine derivative) represented by formula (1):wherein R1, R2, and R3 are as defined above, wherein Rs are the same or different and each represents a C1-C12 alkoxy group optionally substituted with one or more substituents or a C6-C12 aryloxy group optionally substituted with one or more substituents.

The present invention provides a cyano-substituted cyclic hydrazine derivative, comprising: a compound represented by the following structural formula or a stereoisomer, a geometric isomer, a tautomer, a racemate, a hydrate, a solvate, a metabolite and a pharmaceutically acceptable salt or a prodrug thereof The compound is used for prevention, treatment or alleviation of autoimmune diseases or proliferative diseases in patients, and / or for inhibiting or modulating protein kinase activity.

The invention belongs to the technical field of organic synthesis, and particularly relates to a benzenesulfonyl hydrazide derivative, a preparation method and application. Under electrochemical reaction conditions, cheap and easily available ketone, benzenesulfonyl hydrazide and corresponding sodium benzenesulfinate are used as raw materials, acetonitrile (CH3CN) / water (H2O) is used as a solvent, triethylamine (Et3N) is used as alkali, the benzenesulfonyl hydrazide derivative is prepared at room temperature and in an air atmosphere, and the benzenesulfonyl hydrazide derivative has potential medicinal value and is widely applied to the fields of pesticides and medicines. Compared with a previously reported preparation method, the method has the advantages of being green, environmentally friendly, safe, efficient and energy-saving, raw materials are easy to obtain, operation is easy and convenient, and potential industrial application prospects are achieved.

The present application provides a treatment liquid which is excellent in removal of organic residues and excellent in stability. A treatment method of a treated object related to the above treatment liquid is also provided. The treatment liquid contains water, hydroxylamine, and hydrazine species selected from one or more of hydrazine, hydrazine salts, and hydrazine derivatives, and the total content of the hydrazine species is 1 parts by mass or less relative to 100 parts by mass of the hydroxylamine.

The present invention provides a cyano-substituted cyclic hydrazine derivative, comprising: a compound represented by the following structural formula or a stereoisomer, a geometric isomer, a tautomer, a racemate, a hydrate, a solvate, a metabolite and a pharmaceutically acceptable salt or a prodrug thereof. The compound is used for prevention, treatment or alleviation of autoimmune diseases or proliferative diseases in patients, and / or for inhibiting or modulating protein kinase activity.

Provided is a treatment liquid having excellent organic residue removal properties and excellent stability. Also provided is a method for treating an object to be treated using the treatment liquid. The treatment liquid contains water, hydroxylamine, and one or more hydrazine compounds selected from the group consisting of hydrazine, hydrazine salts, and hydrazine derivatives, and the total hydrazine compound content is 1 part by mass or less per 100 parts by mass of hydroxylamine.

The application belongs to the field of medicine, and discloses a compound with the structure of formula I, a preparation method of the compound, and the compound is a pyrazole acylhydrazine derivative containing a diphenyl ether unit, which is obtained by substituting p-chloronitrobenzene with phenol, and then by reduction, diazotization, re-reduction, hydrochloric acid removal and hydrazide reaction; the pyrazole acylhydrazine derivative containing the diphenyl ether unit has obvious inhibitory effect on human pancreatic cancer cells, human breast cancer cells and human gastric cancer cells, and can be used as a potential new type of antitumor candidate drug molecule.

This invention provides a treatment liquid with excellent removal and stability of organic residues. It also provides a method for treating a substance related to the above treatment liquid. The treatment liquid contains water, hydroxylamine, and one or more hydrazines selected from hydrazine, hydrazine salts, and hydrazine derivatives, wherein the total content of the hydrazines is less than 1 part by mass relative to 100 parts by mass of hydroxylamine.

The invention describes a process for producing soluble salts of 5,5-azotetrazole (5,5-AT) by oxidation of 5-aminotetrazole with a soluble peroxodisulfate in a strongly alkaline environment. This compound is a precursor of the energetic component of non-toxic priming mixtures, 5,5- bis-hydrazino-tetrazole (BTH). BTH can be prepared by reduction of salts or solutions of 5,5-AT with ascorbic acid. 5,5-AT

The invention discloses thiazole-2-yl benzoyl hydrazine derivatives as well as a preparation method and application thereof, and belongs to the field of medicinal chemistry. The thiazole-2-yl benzoyl hydrazine derivative shows an excellent broad-spectrum plant pathogenic bacterium resisting effect, has the advantage of being simple in synthesis method, and has important significance on discovery of novel bactericides and overcoming of drug resistance of plant pathogenic fungi.

Provided is a production method comprising step A of reacting a compound represented by Formula (2): wherein R1, R2, and R3 are the same or different, R1 represents -COR, R2 and R3 each represent a hydrogen atom or -COR, and R4 represents a C1-C12 alkyl group or a C6-C12 aryl group; with a fluorinating agent containing IF5, an amine, and HF at 80°C or lower throughout the reaction from the start to the end. This production method is capable of synthesizing a compound (N-fluoroalkylated hydrazine derivative) represented by formula (1): wherein R1, R2, and R3 are as defined above, wherein Rs are the same or different and each represents a C1-C12 alkoxy group optionally substituted with one or more substituents or a C6-C12 aryloxy group optionally substituted with one or more substituents.

Provided is a fiber bundling agent that comprises an aqueous urethane resin composition containing a urethane resin and an aqueous medium, and that is characterized in that: the urethane resin is obtained by using, as essential raw materials, a polyol compound, a diisocyanate compound, a nonionic group-containing compound, and a hydrazine derivative having an active hydrogen atom; the polyol compound includes a polyester polyol; the diisocyanate compound includes an aliphatic diisocyanate compound and / or an alicyclic diisocyanate compound; the nonionic group-containing compound includes polyoxyethylene monomethyl ether and / or polyethylene glycol; and the percentage content of the nonionic group-containing compound is in the range of 3-10 mass% of the raw materials of the urethane resin. The fiber bundling agent exhibits excellent storage stability and bundling properties, generates less pyrolysis gases during molding, and can contribute to yellowing resistance of a formed product.

The invention provides a low-cost and high-plating-speed pure palladium chemical plating solution for a power chip, which comprises the following components based on the total amount of the plating solution: 0.4-0.6 g / L of water-soluble palladium salt, 20-30 g / L of composite complexing agent, 10-20 g / L of pH buffer agent, 8-12 g / L of double reducing agent, 0.1-0.5 g / L of accelerator and 5-8 mg / L of stabilizer, the composite complexing agent comprises 5-10 g / L of organic amines and 15-20 g / L of amino carboxylic acid; the double reducing agents are selected from two of hydrazine substances, formic acid substances or hydroxylamine substances. The chemical palladium plating solution disclosed by the invention can be used for high-speed pure palladium plating in an aluminum substrate chemical nickel-palladium-gold plating surface treatment process on a power chip, an obtained plating layer is a phosphorus-free pure palladium plating layer, the plating speed of the plating solution under the condition of lower palladium content reaches 0.049 mu m / min, the liquid medicine cost and the time cost in the production process can be effectively reduced, and the production efficiency is improved. And meanwhile, the plating solution further has good stability, and stable operation of five MTOs can be achieved.

The application discloses a hydrazide derivative-based carbon dot and a preparation method and application thereof, relates to the technical field of antibacterial materials, and discloses a preparation method, which comprises the following steps: taking a hydrazide derivative as raw material, and preparing a hydrazide derivative-based carbon dot through a one-step hydrothermal method; the hydrazide derivative is at least one of phenylhydrazine, methylhydrazine, isophthalic dihydrazide, thio-diacid hydrazide, salicylic hydrazide, acetic hydrazide, 3-pyridine carbohydrazide, benzhydrazine, p-carboxyphenylhydrazine and carbon hydrazide; the application also protects the hydrazide derivative-based carbon dot prepared through the above method and the application of the hydrazide derivative-based carbon dot in the preparation of antibacterial materials and antibacterial drug resistance materials. The application has the beneficial effect that 10 kinds of hydrazide derivative-based carbon dots are prepared through a simple one-step hydrothermal method with 10 kinds of hydrazide derivatives as precursors; the 10 kinds of hydrazide derivative-based carbon dots all have antibacterial activity, and the carbon hydrazide-based carbon dot shows excellent antibacterial activity and can effectively eradicate biofilms.

The present invention relates to an agrochemical composition comprising, as a herbicidal substance, a combination of a phenylhydrazine derivative and a triketone, a defined solvent, and a surfactant system comprising a non-ionic and an ionic surfactant. The invention also relates to a process for preparing said agrochemical composition, to an agrochemical emulsion or suspension obtainable by diluting said agrochemical composition, and to a method for controlling unwanted vegetation using said agrochemical composition.

The invention provides a chemical mechanical polishing solution for polishing a silicon substrate and capable of improving recycling performance as well as a preparation method and application of the chemical mechanical polishing solution. The chemical mechanical polishing solution at least comprises the following raw material components: an abrasive material, a composite pH regulator, a reducing agent, a dispersing agent, a metal complexing agent and water, the reducing agent comprises one or two of hydrazine derivatives and oxime compounds. The chemical mechanical polishing solution provided by the technical method has the advantages that the removal rate is high, the attenuation degree of the removal rate is small after the chemical mechanical polishing solution is recycled for multiple times, and the color of the chemical mechanical polishing solution is not yellowed after the chemical mechanical polishing solution is recycled for a long time.

The invention discloses a nano-film based on an azetidine hydrazide derivative and a preparation method and fluorescence sensing application thereof, and the nano-film is prepared by taking the azetidine hydrazide derivative and tetraformyl tetraphenylethylene as construction units through a dynamic confinement self-assembly reaction of a gas-liquid interface. By introducing azetidine into hydrazide, the molecular structure can be changed, the electronic configuration can be regulated and controlled, and meanwhile, the system is endowed with specific sensing recognition capability. The preparation method of the nano-film is simple and easy to implement and mild in condition, the size of the film can be accurately regulated and controlled by changing the size of the glass substrate, and convenience is provided for application of the nano-film in large-scale production. The nano-film not only has a flat and smooth surface and good flexibility and self-supporting capability, but also has excellent sensing performance of gaseous nerve poison simulants diethyl chlorophosphate (DCP) and thionyl chloride (SOCl2), shows fluorescence color change from dark to bright, and can realize field detection and distinguishing identification of DCP and SOCl2.

The invention relates to the technical field of pesticides, in particular to an imidazo [1, 2-b] pyridazine-hydrazide derivative, application, a bactericide and a plant pathogenic fungus inhibition method. The compound has a good inhibition effect on various plant pathogenic fungi, is high in inhibition activity, is remarkably superior to other commercially available main bacteriostatic agents, also has the characteristics of high efficiency and low toxicity, and is a candidate compound with a novel skeleton, excellent activity and a wide antibacterial spectrum; the bactericide is wider in application range and better in effect, and can be widely popularized in agricultural production.