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Drug eluting stent and preparing method thereof

A technology for eluting stents and drugs, applied in the field of vascular stents, can solve the problems of uneven stent surface, potential generation, microthrombosis, etc., and achieve the effect of overcoming slow molding speed, good flexibility and ductility

Inactive Publication Date: 2018-03-23
GENERAL HOSPITAL OF PLA
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Moreover, the surface of traditional coated stents is very rough, and when implanted in the body, electric potential and microthrombus can be generated locally.

Method used

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  • Drug eluting stent and preparing method thereof
  • Drug eluting stent and preparing method thereof
  • Drug eluting stent and preparing method thereof

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Embodiment Construction

[0039] Example embodiments will now be described more fully with reference to the accompanying drawings. Example embodiments may, however, be embodied in many forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the concept of example embodiments to those skilled in the art. The same reference numerals in the drawings denote the same or similar structures, and thus their detailed descriptions will be omitted.

[0040] The embodiment of the present invention provides an arterial drug-eluting stent. Of course, those skilled in the art should understand that this stent technology can also be transformed and applied to cardiovascular, peripheral blood vessels, nerve conduits, intestinal tract, bile duct, urethra and bone repair / rebuild app etc.

[0041] In the arterial drug-eluting stent based on 3D printing technology in the embodimen...

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Abstract

The invention relates to an intravascular stent, and discloses a drug eluting stent and a preparing method thereof. The drug eluting stent comprises multiple stent beams, and the stent body is made from a metal material or a biological absorbable material; in the aspect of the cross sections of the stent beams, the drug eluting stent comprises a solid structure body and a drug carrier of a porousstructure, the drug carrier is located at the side, facing the blood vessel wall, of the stent, the drug carrier comprises a surface layer of the outer surface and the porous structure inside, the surface layer is provided with multiple releasing holes, and restenosis and stent thrombosis triggered by the defects of the stent technology can be effectively avoided. The stent porous structure designcan be achieved through a 3D printing technology, and innovative thinking for carrying drugs inside the stent can be completed.

Description

technical field [0001] The present invention generally relates to a vascular stent technology, in particular to a novel arterial drug-eluting stent based on 3D printing technology and a preparation method thereof. Background technique [0002] Since 1987, when Sigwart et al. used intravascular metal stents for coronary arteries for the first time, it has provided a good way for the treatment of vascular occlusion diseases. However, in-stent restenosis and in-stent thrombosis have always affected the The main reason for the efficacy of percutaneous coronary intervention (PCI). The main mechanism of in-stent restenosis is the hyperplasia of vascular intima and the delay of vascular endothelialization. Therefore, the prevention and treatment of in-stent restenosis is mainly to promote the rapid repair of vascular endothelium and inhibit the excessive proliferation of smooth muscle cells. [0003] The currently widely used coronary artery drug-eluting stent (DES) carries drugs ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/90B33Y10/00B33Y80/00A61M31/00
CPCA61F2/90A61M31/002B33Y10/00B33Y80/00
Inventor 白静胡鸢白洁冯宏启沈明志张文勇梅建峰金昕
Owner GENERAL HOSPITAL OF PLA
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