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Rice chaff bran extract and its preparation method and application

A technology of extract and rice bran, which is applied in the field of medicine, can solve the problems such as reports on the application of rice chaff bran extract that have not yet been retrieved

Active Publication Date: 2021-03-26
KUNMING LONGJIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, there are no reports about the application of rice chaff bran extract in improving immune function and lowering lipid

Method used

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  • Rice chaff bran extract and its preparation method and application
  • Rice chaff bran extract and its preparation method and application
  • Rice chaff bran extract and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0137] 10t of rice bran enters the wet extrusion extruder, the saturated steam is injected into the pressure of 0.7MPa, the diameter of the nozzle hole of the template is 10mm, and the expansion ratio is 1:1.1-1.2 to obtain a microporous granular material (100-110°C, moisture 14%), and then use Dry it with a flat dryer until the moisture content is about 6%, and the temperature is 55°C. Add n-hexane at 55°C for leaching for 2 hours at a weight-to-volume ratio of 1:5, filter, and recover the solvent to obtain 1805 kg of crude rice bran oil. Stir and heat the crude rice bran oil to 70°C, add 150L of hot water at 70°C, let it settle for 2 hours, and collect the upper layer of crude rice bran oil. Stir and heat to 70°C, add 100L of hot water at 70°C, add 3L of 85% phosphoric acid, stir for 25min for degumming, let it settle for 5h, collect the upper layer of degummed oil, heat to 100°C, vacuum dry and dehydrate, cool to 80°C, stir Put in 10°C cold water to lower the temperature i...

Embodiment 2

[0145] 10t of rice chaff enters the wet extrusion extruder, the saturated steam is injected into the pressure 0.6MPa, the template nozzle hole diameter is 10mm, and the expansion ratio is 1:1.1-1.2 to obtain microporous granular materials (100-110°C, moisture 13%), Then dry it with a flat dryer until the moisture content is about 6%, and the temperature is 60°C. Add isopropanol for leaching at 60°C for 2 hours at a weight-to-volume ratio of 1:7, recover the solvent, and obtain 1886 kg of crude rice bran oil. Stir and heat the crude rice bran oil to 70°C, add 150L of hot water at 70°C, let it settle for 2 hours, and collect the upper layer of crude rice bran oil. Stir and heat to 70°C, add 100L of hot water at 70°C, add 3L of 85% phosphoric acid, stir for 30min for degumming, let it settle for 4h, collect the upper layer of degummed oil, heat to 100°C, vacuum dry and dehydrate, cool to 70°C, stir Pass in 10°C cold water to lower the temperature indirectly, lower the temperatur...

Embodiment 3

[0148]10t of rice bran enters the wet extrusion extruder, the saturated steam is injected into the pressure of 0.8MPa, the diameter of the nozzle hole of the template is 10mm, and the expansion ratio is 1:1.1-1.2 to obtain a microporous granular material (100-110°C, moisture 14%), and then use Dry it with a flat-plate dryer until the water content is about 6%, add isopropanol at 60°C for 2 hours at a weight-to-volume ratio of 1:7, and recover the solvent to obtain 1888 kg of crude rice bran oil. Stir and heat the crude rice bran oil to 70°C, add 150L of hot water at 70°C, let it settle for 2 hours, and collect the upper layer of crude rice bran oil. Stir and heat to 70°C, add 100L of hot water at 70°C, add 3L of oxalic acid, stir for 25min for degumming, let it settle for 5h, collect the upper layer of degummed oil, heat to 100°C, vacuum dry and dehydrate, cool to 80°C, stir and pour into 10 Cool the temperature with cold water indirectly to 20-25°C, continue to stir slowly at...

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Abstract

The invention relates to the field of medicine, in particular to rice chaff extract, preparation method thereof and application of the rice chaff extract in medicine and health foods. The rice chaff extract comprises, by weight, 50-90% of 1-triacontanol, 1-20% of 1-octacosanol and 5-30% of 1-dotriacontanol. The rice chaff extract is extracted from rice chaff. The rice chaff extract can enhance immunity; the results prove that the rice chaff extract can significantly promote the generation of mouse hemolysin antibody, phagocytosis of mouse peritoneal macrophage and proliferation of mouse splenic lymphocytes. The rice chaff extract can activate activity of mouse NK cells and is significantly antagonistic to the reduction in the quantity of white cells in a mouse with cyclophosphamide-inducedLewis lung cancer. In addition, the rice chaff extract can significantly lower serum TC, TG and LDL-C levels in hyperlipidemia rats. The invention relates to application of the rice chaff extract inthe preparation of medicine and health products, particularly in the preparation of medicine and health products to enhance immunity and lower blood lipid.

Description

technical field [0001] The invention relates to the field of medicine, in particular to rice chaff bran extract, a preparation method and application in medicine and health food. Background technique [0002] my country is a big rice producing country, and the annual rice output accounts for about 30% of the world's total output. As a by-product of rice processing, rice bran has a large yield and high extraction and utilization value. Its functions and indications are recorded in the "Rice Chaff Bran Medicinal Material Standard" drafted by Kunming Longjin Pharmaceutical Co., Ltd. and reviewed by Yunnan Food and Drug Inspection Institute: invigorating the spleen and appetizing, digestion and accumulation, lowering Qi and clearing the intestines; treating beriberi; For loss of appetite, choking diaphragm, nausea, indigestion; beriberi. [0003] Chinese patent application No. 93109943.9 discloses a "total alkanol for blood lipid reduction", which is a mixture of octacosanol t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A23L33/105A61P37/04A61P3/06
CPCA23V2002/00A61K36/899A61K2236/17A61K2236/33A61K2236/35A61K2236/51A61K2236/53A23L33/105A23V2200/324A23V2200/3262A23V2250/21
Inventor 王昆樊献俄张伟武鸿萍段银孙继福杨春雷
Owner KUNMING LONGJIN PHARMA