Colorectal cancer microbial marker and application thereof

Abstract

The invention provides a colorectal cancer microbial marker and application thereof. The colorectal cancer microbial marker comprises microorganism, wherein the microorganism comprises any one or a combination of at least two of Treptococcus bovis, Clostridium septicum, Parvimonas micra and Helicobacter pylori. The colorectal cancer microbial marker provided by the invention has the potential of being used as a colorectal cancer marker, the content of the colorectal cancer microbial marker in an excrement sample of a patient suffering from colorectal cancer is remarkably higher than the content of the colorectal cancer microbial marker in an excrement sample of a healthy individual, statistical significance is obtained, whether an individual suffers from the colorectal cancer or not can berelatively accurately determined, and a colorectal cancer non-invasively auxiliary diagnosis function is obtained.

Description

technical field

[0001] The invention belongs to the field of microorganisms, and relates to a colorectal cancer microbial marker and application thereof. Background technique

[0002] Colorectal cancer is one of the most common malignant tumors of the digestive tract. The number of new cases worldwide is about 1 million per year, and the death toll is about 500,000. With the improvement of people's living standards and changes in eating habits, colorectal cancer has become one of the fastest-growing malignant tumors in my country, with about 140,000 new cases each year, accounting for 6.8% of all cancer patients. Tumor ranks 4th. It is predicted that colorectal cancer will become one of the most common malignant tumors in my country, and its morbidity and mortality will continue to rise for a long period of time in the future. Although comprehensive treatment methods such as surgery, chemotherapy, and radiotherapy have been used in the treatment of colorectal cancer, about ...