Supercharge Your Innovation With Domain-Expert AI Agents!

Absorbable medical suture thread

A suture, chitosan technology, applied in medical science, surgery, surgical instruments, etc., can solve the problems of secondary injury, loss, and weakened suture function of patients, and achieve the effect of improving mechanical strength and increasing stability

Inactive Publication Date: 2018-04-24
庞振方
View PDF6 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Among the absorbable sutures, the suture made of chitosan as the main material is a relatively commonly used absorbable suture. Chitosan has good biocompatibility and has good chemical inertness and certain antibacterial properties. It can reduce the chance of suture wound infection, but the mechanical strength of chitosan is not high. After the surgical suture made of chitosan is implanted into the human body through surgical suture, the suture will begin to degrade gradually, and the mechanical strength of the suture It will also decline, weakening or prematurely losing the function of the suture, causing the degradation rate of the suture to fail to match the healing speed of the wound, and even causing secondary damage to the patient due to the premature loss of the function of the suture. In order to provide A suture that does not affect degradation and has high mechanical strength, the invention provides the following technical solutions

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The purpose of the present invention can be achieved through the following technical solutions:

[0022] An absorbable medical suture, prepared from the following raw materials: 80 parts of modified chitosan, 10 parts of polyglycolic acid, 5 parts of polyvinylpyrrolidone, 0.5 parts of oregano oil, 0.2 parts of thymol and castor oil 2 servings.

[0023] Further, the preparation method of modified chitosan is: adding chitosan to citric acid and stirring to dissolve at a water bath temperature of 50°C, adding polyethylene glycol, ethylene glycol dimethacrylate and methacrylic acid hydroxyl Propyl ester, ultrasonic treatment for 15min, standing for 2h, adding excess absolute ethanol to obtain a precipitate, suction filtration to obtain a filter cake, washing the filter residue 3 times with 2% aqueous sodium hydroxide solution, washing with deionized water until neutral, vacuum drying, passing Sieve to obtain the dry filter residue, soak in the soaking solution for 20 hours...

Embodiment 2

[0029] The purpose of the present invention can be achieved through the following technical solutions:

[0030] An absorbable medical suture, prepared from the following raw materials: 100 parts of modified chitosan, 15 parts of polyglycolic acid, 5 parts of polyvinylpyrrolidone, 0.5 parts of oregano oil, 0.3 parts of thymol and castor oil 2.5 servings.

[0031] Further, the preparation method of modified chitosan is: adding chitosan to citric acid and stirring to dissolve at a water bath temperature of 60° C., adding polyethylene glycol, ethylene glycol dimethacrylate and methacrylic acid hydroxyl Propyl ester, ultrasonic treatment for 12min, standing for 1.5h, adding excess absolute ethanol to obtain a precipitate, suction filtration to obtain a filter cake, washing the filter residue 4 times with 2% aqueous sodium hydroxide solution, washing with deionized water until neutral, and vacuum drying , sieved to obtain dry filter residue, soaked in soaking solution for 24 hours,...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an absorbable medical suture thread. The absorbable medical suture thread is prepared from 80-100 parts of modified chitosan, 8-15 parts of polyglycolic acid, 4.5-7 parts of polyvinylpyrrolidone, 0.5-0.8 part of origanum oil, 0.2-0.35 part of thymol and 1.5-3 parts of castor oil. The preparing method of modified chitosan comprises the steps of adding polyethylene glycol, ethylene glycol dimethacrylate and hydroxypropyl methacrylate into a citric acid solution of chitosan, conducting ultrasonic treatment and purification to obtain an intermediate material, adding the intermediate material into a first solvent, adding polylactic acid, and conducting ultrasonic treatment, high speed stirring, freezing, vacuum drying and screening to obtain modified chitosan. By means of the absorbable medical suture thread, chitosan is modified, on the premise of not seriously influencing the flexibility of fiber prepared from chitosan, the mechanical strength of the suture threadis improved, and polyglycolic acid, polyvinylpyrrolidone and castor oil can improve the stability of the suture thread.

Description

technical field [0001] The invention belongs to the field of medical material processing, and in particular relates to an absorbable medical suture. Background technique [0002] Medical suture refers to a special thread used for wound suture hemostasis and tissue suture in surgical operations. According to the biodegradability of suture, suture can be mainly divided into two categories: non-absorbable thread and absorbable thread. The current medical sutures are mainly absorbable threads. [0003] Among the absorbable sutures, the suture made of chitosan as the main material is a relatively commonly used absorbable suture. Chitosan has good biocompatibility and has good chemical inertness and certain antibacterial properties. It can reduce the chance of suture wound infection, but the mechanical strength of chitosan is not high. After the surgical suture made of chitosan is implanted into the human body through surgical suture, the suture will begin to degrade gradually, a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61L17/10A61L17/00A61L17/12
CPCA61L17/005A61L17/10A61L17/12A61L2300/232A61L2300/404C08L5/08C08L39/06C08L71/02
Inventor 庞振方
Owner 庞振方
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com