Traditional Chinese medicine composition and traditional Chinese medicine preparation for treating ischemic stroke and application thereof
A technology of ischemic stroke and traditional Chinese medicine preparations, which is applied in the direction of drug combinations, non-central analgesics, medical preparations containing active ingredients, etc. It can solve the problems of complex formulas and large dosages, and achieve increased blood flow and better efficacy. Excellent, anti-oxidation and free radical scavenging and platelet aggregation effect
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Embodiment 1
[0036] The preparation of embodiment 1 capsule
[0037] prescription:
[0038] Astragalus: 240 parts, Angelica: 480 parts, Corydalis: 420 parts, Achyranthes bidentata: 125 parts, and Curcuma: 230 parts.
[0039] Preparation Process:
[0040] 1) Take curcuma decoction pieces, dry at 80°C, crush into fine powder, pass through a 100-mesh sieve, add 75% ethanol to moisten, and place in airtight for 12 hours, and set aside.
[0041] 2) Take angelica decoction pieces, add 8 times the amount of 75% ethanol, reflux extraction twice, each time for 2 hours, filter, combine the filtrates twice, recover ethanol under reduced pressure, concentrate into an extract with a relative density of 1.20, extract Add ethanol for precipitation, so that the alcohol content is 75%, stand for 24 hours, take the supernatant to recover ethanol under reduced pressure, concentrate into a thick paste with a relative density of 1.30, and store it in a cold storage for future use.
[0042]3) Take Astragalus...
Embodiment 2
[0046] The preparation of embodiment 2 tablet
[0047] prescription:
[0048] Astragalus: 240 parts, Angelica: 480 parts, Corydalis: 420 parts, Achyranthes bidentata: 125 parts, and Curcuma: 230 parts.
[0049] Preparation Process:
[0050] 1) Take the curcuma decoction pieces, dry them at 80°C, crush them into fine powder, pass through a 100-mesh sieve, add 75% ethanol to moisten them, place them in airtight storage for 12 hours, and set aside.
[0051] 2) Take angelica decoction pieces, add 8 times the amount of 75% ethanol, reflux extraction twice, each time for 2 hours, filter, combine the filtrates twice, recover ethanol under reduced pressure, concentrate into an extract with a relative density of 1.20, extract Add ethanol for precipitation, so that the alcohol content is 75%, stand for 24 hours, take the supernatant to recover ethanol under reduced pressure, concentrate into a thick paste with a relative density of 1.30, and store it in a cold storage for future use. ...
Embodiment 3
[0056] Example 3 Corydalis Corydalis Extraction Process Investigation
[0057] Corydalis Corydalis was taken and extracted according to the process conditions in Table 1. Corydalin, one of the alkaloids as the active ingredient, was used as a marker to measure its content. The results are shown in Table 1.
[0058] Table 1
[0059]
[0060]
[0061] It can be seen from the results in Table 1 that the boiling extraction method can increase the active ingredient content in the extract compared with the ethanol reflux extraction method, and the boiling and alcohol precipitation extraction method can further increase the tetrahydropalmatine content in the extract. The best extraction process is to extract 2 times with 8 times the amount of water for 2 hours each time, and then alcohol precipitation.
[0062] Furthermore, the boiling was replaced by "acid water" extraction, and 8 times the amount of solvent was extracted twice, each time for 2 hours, the results are shown in...
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