Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

N-vinyl pyrrolidone and N-vinyl caprolactam random copolymer solution and preparation method thereof

A technology of vinylpyrrolidone and vinylcaprolactam, which is applied in the field of free radical solution polymerization, and can solve problems such as product safety impact and limited use range

Active Publication Date: 2018-07-27
BOAI NKY PHARMA LTD
View PDF12 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In the above-mentioned methods, it is impossible to obtain a clear aqueous solution with only two structural unit copolymers of NVP and NVCL. Due to the introduction of other crosslinking agents or monomers, the safety of the product is affected, thereby limiting its scope of use.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • N-vinyl pyrrolidone and N-vinyl caprolactam random copolymer solution and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Put 450 parts of ethanol, 18 parts of NVP, and 90 parts of NVCL into the reactor, slowly raise the temperature to 55°C under vigorous stirring, add 22.5 parts of azobisisobutyronitrile immediately after reaching the temperature, and start adding 342 parts of NVP. Dosing is completed within 8 hours. After that, 0.3 part of azobisisobutyronitrile was added and kept at a constant temperature for 5 hours, and the reaction was completed. Ethanol in the reaction solution was evaporated under reduced pressure using a rotary evaporator, and then 1800 parts of water was added for further evaporation to finally obtain a random copolymer solution with a solid content of 30 wt%.

Embodiment 2

[0040] Put 65 parts of water, 195 parts of ethanol, 18 parts of NVP, and 20 parts of NVCL into the reactor, slowly raise the temperature to 65°C under vigorous stirring, add 0.50 parts of azobisisobutyronitrile immediately after the temperature reaches, and start adding 78 parts of NVP, This part of NVP was added within 1.5 hours. After that, 0.06 part of azobisisobutyronitrile was added and kept at a constant temperature for 5 hours, and the reaction was completed. The water and ethanol in the reaction liquid were evaporated under reduced pressure using a rotary evaporator, and then 250 parts of water were added for further evaporation to finally obtain a random copolymer solution with a solid content of 30%.

Embodiment 3

[0042] Put 102 parts of water, 918 parts of isopropanol, 18 parts of NVP, and 160 parts of NVCL into the reactor, slowly raise the temperature to 60°C under vigorous stirring, add 0.50 parts of pivalate peroxide immediately after the temperature reaches, and start adding NVP162 Parts, this part of NVP is added within 1.0 hours. After that, 0.18 parts of peroxypivalic acid ester was added and kept at a constant temperature for 3 hours, and the reaction was completed. The water and isopropanol in the reaction solution were evaporated under reduced pressure using a rotary evaporator, and then 2000 parts of water were added for further evaporation to finally obtain a random copolymer solution with a solid content of 50 wt%.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides an N-vinyl pyrrolidone and N-vinyl caprolactam random copolymer solution and a preparation method thereof. The random copolymer solution is a homogeneous solution of the binaryrandom copolymer of N-vinyl pyrrolidone (NVP) and N-vinyl caprolactam, the random copolymer comprises 20 wt%-80 wt% of NVP and 20 wt%-80 wt% of NVCL, the solid content of the copolymer solution is 10wt%-50 wt%, and a cloud point is 39 DEG C-92 DEG C. The obtained random copolymer solution of N-vinyl pyrrolidone and N-vinyl caprolactam is clear and transparent under room temperature, the viscosityis 2000 cP-25000 cP, and the cloud point can be adjusted at 39 DEG C-92 DEG C.

Description

technical field [0001] The present invention relates to a random copolymer solution of N-vinylpyrrolidone and N-vinylcaprolactam and a preparation method thereof. The copolymer is a binary homogeneous copolymer of N-vinylpyrrolidone and N-vinylcaprolactam , the polymerization method involved is free radical solution polymerization. Background technique [0002] Poly(N-vinylcaprolactam) (PNVCL) has low toxicity, good temperature sensitivity, biocompatibility and biodegradability. Its lower critical solution temperature (LCST) can be regulated by the length of the polymer chain segment and the concentration of the solution, and it has a wide range of applications in the field of biomedicine. Poly N-vinylpyrrolidone (PVP) has been approved by the FDA as a food additive, and has the characteristics of low toxicity, good water solubility and biocompatibility. [0003] The temperature sensitivity mainly depends on the proportion of hydrophobic groups and hydrophilic groups in th...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C08F226/06C08F226/10C08F2/00
CPCC08F2/00C08F226/06C08F226/10
Inventor 孙旭东牛磊张森林
Owner BOAI NKY PHARMA LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com