The invention discloses a compound bifonazole nano-
emulsion spray preparation. The nano-
emulsion spray preparation has the grain size of 1 nm to 100 nm and is formed by the following raw materials in
mass percent: 30%-40% of surfactant, 3%-14% of cosurfactant, 5%-10% of
oil phase, 0.8%-2% of bifonazole, 0.02%-0.1% of
clobetasol propionate, 0.01%-0.2% of cinnamyl
aldehyde and the balance of deionized water, wherein the sum of the
mass percents of the raw materials is 100%. The compound bifonazole nano-
emulsion spray preparation has multiple actions, such as
fungicide, bactericide, anti-bacterial, anti-fungal, antiinflammation,
itching relieving and the like, treats superficial
skin fungous infection, fungous paronychia and candidal vulvovaginitis, and is also effective to external
otitis and bacterial
skin infection. The compound bifonazole nano-emulsion spray preparation prepared by a preparation method of the compound bifonazole nano-emulsion spray preparation has the advantages that: the activity of the three drugs is remarkably improved, the effect of sterilization and
itching relieving is rapid, the recurrence is difficult, and the preparation method is simple, so that the compound bifonazole nano-emulsion spray preparation and the preparation method thereof have broad market prospects in the
medicine field.