SNP molecular marker of fam131c gene related to bone mineral density of sow limbs and hoofs

A technology of molecular markers and bone density, applied in the direction of DNA/RNA fragments, recombinant DNA technology, microbial measurement/inspection, etc., can solve problems such as economic losses in pig farms, and achieve high sensitivity and good specificity
CN108384864BActive Publication Date: 2021-06-01HUAZHONG AGRI UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HUAZHONG AGRI UNIV
Publication Date
2021-06-01

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Abstract

The invention belongs to the field of animal molecular marker screening, in particular to the SNP molecular marker of the FAM131C gene related to the bone density of sow limbs and hooves. Through genotyping technology and referring to the Ensembl database, the FAM131C gene fragment with the accession number ASGA0099279 gene upstream and downstream 100 bp sequence was obtained, and the sequence is shown in SEQ ID NO:1. The FAM131C gene was typed using gene chip technology, and the markers related to the bone density of sow limbs and hooves were screened. Its sequence is shown in SEQ ID NO: 1, and the R at the 101st base of the above sequence is C or T , leading to polymorphisms in nucleotide sequences. It can be used as a molecular marker for detection of porcine bone density. When the 101st nucleotide on SEQ ID NO: 1 is C, the sow's limbs and hooves have higher bone density. The invention provides a new SNP marker for marker-assisted selection of porcine bone density.
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Description

technical field

[0001] The invention belongs to the technical field of animal molecular marker screening, in particular to a SNP molecular marker of the FAM131C gene related to the bone density of sow limbs and hooves. The molecular marker of the invention can be used for detection of bone density traits of pig limbs and hooves. Background technique

[0002] my country is a big pork consumer, and the hog industry is an important part of our national economy. In order to improve the production level of our country's hogs and meet the growing domestic demand for lean meat, a large number of lean meats such as Duroc, Landrace, and Large White are introduced from abroad every year. Meat type pig. In my country's intensive breeding environment, these pigs are prone to limb and foot disease, lameness and even paralysis, resulting in early elimination of breeding pigs. Leg disease in sows can delay estrus or affect the symptoms of estrus, prolong the time of empty pregnancy, sows ...

Claims

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