Pancreatic duct adenocarcinoma marker and application thereof

A pancreatic ductal adenocarcinoma and biomarker technology, applied in the field of tumor diagnosis and molecular targeted therapy, can solve the problems of only 15%, less than 20% survival rate, easy recurrence and metastasis, etc.
CN108456733AInactive Publication Date: 2018-08-28THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIV
Publication Date
2018-08-28
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a pancreatic duct adenocarcinoma related tumor marker LINC01133, and application of a kit for detecting expression level of LINC01133 in the detection and diagnosis of pancreatic duct adenocarcinoma or patient prognostic evaluation. The expression level of LINC01133 is closely related to the clinical pathological parameters of pancreatic duct adenocarcinoma and the patientprognosis, and can be adopted as a specific tumor marker in pancreatic duct adenocarcinoma detection and a prognostic indicator, and thus is of an important clinical value.
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Description

technical field

[0001] The invention belongs to the field of tumor diagnosis and molecular targeted therapy, and relates to a tumor marker related to pancreatic ductal adenocarcinoma and its application. Background technique

[0002] In recent years, the incidence of pancreatic ductal adenocarcinoma (Pancreatic Duct Adenocarcinoma) has been increasing year by year worldwide. Due to the high degree of malignancy and rapid progression of pancreatic cancer, its prognosis is extremely poor, and the overall 5-year survival rate is less than 5%. Although radical surgical resection can improve the prognosis and increase the long-term survival rate, due to the hidden onset, rapid progression, and easy recurrence and metastasis of pancreatic cancer, the radical surgical resection rate is only 15%, and the 5-year survival rate after surgery is insufficient. 20%. In addition, pancreatic cancer still lacks specific chemotherapy drugs and targeted therapy drugs, which are not highly se...

Claims

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