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Anesthetic with low side effect and preparation method thereof

A side effect and anesthetic technology, applied in the field of low side effect anesthetic and its preparation, can solve problems such as large side effects and patient discomfort, and achieve the effects of low side effects, reduced treatment costs, and long duration of anesthesia block.

Inactive Publication Date: 2018-09-21
赵涛
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the existing anesthetics have relatively large side effects. The most common effects of anesthetics include chills, nausea, arrhythmia, etc., which bring great discomfort to the patient.

Method used

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  • Anesthetic with low side effect and preparation method thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0018] An anesthetic with low side effects, comprising the following raw materials: polyhexamethyleneguanidine 0.1g, ephedrine 0.3g, ketamine hydrochloride 0.2g, lutein 1g, Tween 80 5g, droperidol 1g, lidocaine 0.2g, Glucose 2g, distilled water 100g.

[0019] A method for preparing an anesthetic with low side effects, comprising the following steps: (1) weighing the raw materials of each component according to the number of parts for use; (2) taking half of the distilled water, adding lutein and Tween 80 to the distilled water, and microwave , to obtain lutein emulsion; (3) adding polyhexamethylene guanidine and ephedrine to lutein emulsion, sealing and stirring for 10min, to obtain configuration solution A; (4) taking the other half of distilled water, adding ketamine hydrochloride, dropperidin Add lidocaine and lidocaine into distilled water, heat and stir at a heating temperature of 35°C to obtain configuration solution B; (5) Mix configuration solution A and configuration ...

Embodiment 2

[0021] An anesthetic with low side effects, comprising the following raw materials: polyhexamethyleneguanidine 0.5g, ephedrine 0.8g, ketamine hydrochloride 0.6g, lutein 5g, Tween 80 10g, droperidol 5g, lidocaine 0.8g, Glucose 10g, distilled water 200g.

[0022] A method for preparing an anesthetic with low side effects, comprising the following steps: (1) weighing the raw materials of each component according to the number of parts for use; (2) taking half of the distilled water, adding lutein and Tween 80 to the distilled water, and microwave , to obtain lutein emulsion; (3) adding polyhexamethylene guanidine and ephedrine to lutein emulsion, sealing and stirring for 20min, to obtain configuration solution A; (4) taking the other half of distilled water, adding ketamine hydrochloride, dropperidin Add lidocaine and lidocaine into distilled water, heat and stir at 45°C to obtain configuration solution B; (5) Mix and stir configuration solution A and configuration solution B for...

Embodiment 3

[0024] An anesthetic with low side effects, comprising the following raw materials: polyhexamethyleneguanidine 0.2g, ephedrine 0.4g, ketamine hydrochloride 0.3g, lutein 2g, Tween 80 6g, droperidol 2g, lidocaine 0.3g, Glucose 4g, distilled water 120g.

[0025] A method for preparing an anesthetic with low side effects, comprising the following steps: (1) weighing the raw materials of each component according to the number of parts for use; (2) taking half of the distilled water, adding lutein and Tween 80 to the distilled water, and microwave , to obtain lutein emulsion; (3) adding polyhexamethylene guanidine and ephedrine to lutein emulsion, sealing and stirring for 15min, to obtain configuration solution A; (4) taking the other half of distilled water, adding ketamine hydrochloride, dropperidin Add lidocaine and lidocaine into distilled water, heat and stir at a heating temperature of 38°C to obtain configuration solution B; (5) Mix and stir configuration solution A and confi...

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PUM

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Abstract

The invention discloses an anesthetic with low side effect and a preparation method thereof. The anesthetic is prepared from raw materials of, by weight, 0.1-0.5 part of polyhexamethylene guaidine hydrochloride and phosphate, 0.3-0.8 part of ephedrine, 0.2-0.6 part of ketamine hydrochloride, 1-5 parts of xanthophyll, 5-10 parts of Tween 80, 1-5 parts of droperidol, 0.2-0.8 part of lidocaine, 2-10parts of glucose, and 100-200 parts of distilled water. The anesthetic has low side effect, has long anesthesia blocking duration and greatly reduces risk in general anesthesia of patients. The preparation method is simple, achieves high economic benefit, and reduces treatment cost for patients.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to an anesthetic with low side effects and a preparation method thereof. Background technique [0002] Anesthetics refer to drugs or non-drug methods that temporarily reversibly lose consciousness and pain in the body or parts of the body, and are mostly used in surgery or the treatment of certain diseases. Hua Tuo, a famous medical scientist in ancient my country, invented "Mafeisan", which is the first anesthetic invented and used in the world. Our country has used "Mabeisan" general anesthesia for laparotomy. Mafeisan was selected as the world's earliest anesthetic by the World Records Association; Hua Tuo was selected by the World Records Association as the world's first person to use anesthesia for surgery. Mafeisan created the world's best in ancient Chinese medicine. [0003] The person who first invented general anesthetics in modern times was the British chemist ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/785A61K31/137A61K31/135A61K31/047A61K31/4439A61K31/167A61P23/00
CPCA61K31/047A61K31/135A61K31/137A61K31/167A61K31/4439A61K31/785A61P23/00A61K2300/00
Inventor 赵涛
Owner 赵涛