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Chinese medicinal granules for treating chronic pelvic inflammation and preparation process thereof

A technology of chronic pelvic inflammatory disease and traditional Chinese medicine granules, applied to medical preparations containing active ingredients, diseases, drug combinations, etc., to achieve the effects of strong practicability, stable product quality, and low energy consumption

Inactive Publication Date: 2018-09-21
三亚市妇幼保健院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The development of compound Chinese medicine preparations with multi-components that reduce toxicity and increase efficacy is becoming a new hot spot in the future world pharmaceutical market. There are many types of drugs for the treatment of chronic pelvic inflammatory disease that are currently on the market, but not all of them are effective for all patients.

Method used

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  • Chinese medicinal granules for treating chronic pelvic inflammation and preparation process thereof
  • Chinese medicinal granules for treating chronic pelvic inflammation and preparation process thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A kind of Chinese medicine granule for the treatment of chronic pelvic inflammatory disease, its preparation process comprises the following steps:

[0028] 1) Take the following medicinal materials in parts by weight: Astragalus 2kg, Codonopsis 1kg, Angelica 0.5kg, Radix Paeoniae Rubra 0.5kg, Red Teng 1kg, Patrinia 1kg, Toosendan 0.5kg, Rhizoma Cyperi 0.5kg, Motherwort 1kg, Salvia miltiorrhiza 0.5kg , trigonum 0.5kg, licorice 0.3kg;

[0029] 2) Astragalus, Codonopsis, Toosendan, and Glycyrrhiza were crushed through a 60-mesh sieve to obtain a coarse powder, which was soaked in water twice the total amount of the four medicinal materials for 1 hour, placed in a water bath at 55°C, and the pH was adjusted with 1mol / L hydrochloric acid To 4, weigh 3% cellulase with added water, add it to the supernatant with adjusted pH, enzymolyze it for 100 minutes, transfer it to a water bath at 100°C to kill the enzyme, centrifuge at 4000r / min for 10min, and use it for precipitation ...

Embodiment 2

[0033] A kind of Chinese medicine granule for the treatment of chronic pelvic inflammatory disease, its preparation process comprises the following steps:

[0034] 1) Take the following medicinal materials in parts by weight: Astragalus 4kg, Codonopsis 3kg, Angelica 2kg, Radix Paeoniae Rubra 2kg, Red Vine 2.5kg, Patrinia 2.5kg, Toosendan 1.5kg, Rhizoma Cyperi 1.5kg, Motherwort 2.5kg, Salvia miltiorrhiza 2kg , trigonum 2kg, licorice 1kg;

[0035] 2) Astragalus, Codonopsis, Toosendan, and Glycyrrhizae were crushed through a 30-mesh sieve to obtain a coarse powder, which was soaked in water 4 times the total amount of the four medicinal materials for 1 hour, placed in a water bath at 55°C, and the pH was adjusted with 1mol / L hydrochloric acid To 4, weigh 8% of the mass of cellulase added with water, add it to the supernatant whose pH has been adjusted, enzymolyze it for 120 minutes, transfer it to a water bath at 100°C to kill the enzyme, centrifuge at 4000r / min for 15min, and us...

Embodiment 3

[0039] A kind of Chinese medicine granule for the treatment of chronic pelvic inflammatory disease, its preparation process comprises the following steps:

[0040] 1) Take the following medicinal materials in parts by weight: Astragalus 2.5kg, Codonopsis 1.5kg, Angelica 0.8kg, Radix Paeoniae Rubra 0.8kg, Red Rattan 1.2kg, Patrinia 1.2kg, Toosendan 0.7kg, Rhizoma Cyperi 0.7kg, Motherwort 1.2kg kg, Danshen 0.8kg, trigonum 0.8kg, licorice 0.5kg;

[0041] 2) Astragalus, Codonopsis, Toosendan, and Glycyrrhizae were crushed through a 40-mesh sieve to obtain a coarse powder, which was soaked in water twice as much as the total amount of the four medicinal materials for 1 hour, placed in a water bath at 55°C, and the pH was adjusted with 1mol / L hydrochloric acid To 4, weigh 4% cellulase with added water, add it to the supernatant that has been adjusted in pH, enzymolyze it for 110 minutes, transfer it to a water bath at 100°C to kill the enzyme, centrifuge at 4000r / min for 12min, and ...

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Abstract

The invention relates to Chinese medicinal granules for treating chronic pelvic inflammation and a preparation process of the Chinese medicinal granules for treating the chronic pelvic inflammation. The Chinese medicinal granules are prepared from the following raw materials: radix astragali, radix codonopsis pilosulae, szechwan chinaberry fruit, radix glycyrrhizae, radix angelicae sinensis, radixpaeoniae rubra, caulis sargentodoxae, herba patriniae, rhizoma cyperi, herba leonuri, radix salviae miltiorrhizae and rhizoma sparganii. The invention further provides a preparation method of the Chinese medicinal granules. The Chinese medicinal granules are prepared by dry granulation, so that the preparation method has the characteristics of significantly reduced use amount of auxiliary materials, stable product quality, high production efficiency, low cost, low energy consumption, strong practicality and the like.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine granule for treating chronic pelvic inflammatory disease and a preparation process thereof. Background technique [0002] Chronic pelvic inflammatory disease (CPID) refers to the chronic inflammation of female reproductive organs, surrounding connective tissue and poor peritoneum. . The main clinical features are abdominal pain, abnormal leukorrhagia, thickening of pelvic tissue, adhesion, and mass formation. Inflammation can be confined to one position, and can also involve several positions at the same time. It often recurs and is lingering and difficult to heal. It is one of the common causes of ectopic pregnancy and infertility. In recent years, the incidence of chronic pelvic inflammatory disease has been increasing year by year, and has become a common and multiple gynecological disease. [0003] Western medicine bel...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/902A61K9/16A61P15/00
CPCA61K9/1652A61K36/185A61K36/232A61K36/344A61K36/48A61K36/481A61K36/484A61K36/486A61K36/533A61K36/537A61K36/58A61K36/65A61K36/71A61K36/84A61K36/8905A61K36/902A61K2236/19A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 孙臻周玉海高华宏汪杰黄敏张影薛中峰黎俊禹黄祖光陈明聪陈焕擂
Owner 三亚市妇幼保健院