Unlock instant, AI-driven research and patent intelligence for your innovation.

A composite catalyst for synthesizing tetrahydrofuran-3-carbaldehyde and method for using it to synthesize tetrahydrofuran-3-carbaldehyde

A composite catalyst, tetrahydrofuran technology, applied in organic compound/hydride/coordination complex catalysts, chemical instruments and methods, physical/chemical process catalysts, etc. expensive effect

Active Publication Date: 2020-11-24
HEBEI VEYONG BIO CHEM
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to overcome the defects of the prior art and provide a composite catalyst for the synthesis of tetrahydrofuran-3-carbaldehyde, which not only overcomes the problems of high cost and harsh reaction conditions in traditional noble metal catalysts, but also improves the reaction yield and optional

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] 150g of 2,5-dihydrofuran was added to a 1L autoclave, 308g of tetrahydrofuran (with a water content of 0.1%) was added, and the catalyst HCCo 3 (CO) 9 1.5g, Fe(CO) 5 1.5g and 12g of tetrabutylammonium chloride, after passing through hydrogen to replace the air in the reactor, then passing through hydrogen at 0.5MPa, carbon monoxide at 0.5MPa, heating to 60°C, and reacting for 50h. After the reaction, the solvent tetrahydrofuran was evaporated under normal pressure for recycling, and then the product tetrahydrofuran-3-carbaldehyde was distilled under reduced pressure, with a purity of 98% and a yield of 90.6%. The remaining catalyst is recovered and applied mechanically.

Embodiment 2

[0023] Add 150 g of 2,5-dihydrofuran into a 1L autoclave, add 308 g of tetrahydrofuran (the mass fraction of water is 0.3%), and add the catalyst HCCo 3 (CO) 9 12g, Fe(CO) 5 9g and 1.5g of tetrabutylammonium chloride, after passing through hydrogen to replace the air in the reactor, then passing through hydrogen at 2.0MPa, carbon monoxide at 4.0MPa, heating to 120°C, and reacting for 3h. After the reaction, the solvent tetrahydrofuran was distilled off under normal pressure for recycling, and then the product tetrahydrofuran-3-carbaldehyde was distilled under reduced pressure, with a purity of 98% and a yield of 89.2%. The remaining catalyst is recovered and applied mechanically.

Embodiment 3

[0025] Add 150 g of 2,5-dihydrofuran and 1,508 g of methyl tert-butyl ether (the mass fraction of water is 0.1%) into a 2L autoclave, and add the catalyst ClCCo 3 (CO) 9 6g, Fe(OAc) 2 6g and 4.5g of dodecyltrimethylammonium chloride, after passing through hydrogen to replace the air in the kettle, then passing through hydrogen at 1.5MPa, carbon monoxide at 1.5MPa, heating to 80°C, and reacting for 40h. After the reaction was completed, the solvent methyl tert-butyl ether was distilled off under normal pressure for recycling, and then the product tetrahydrofuran-3-carbaldehyde was distilled out under reduced pressure, with a purity of 97% and a yield of 93.3%. The remaining catalyst is recovered and applied mechanically.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a composite catalyst for synthesizing tetrahydrofuran-3-formaldehyde, including a cobalt cluster compound RCCo 3 (CO) 9 , iron compounds and quaternary ammonium salts R 1 3 R 2 NCl or quaternary phosphonium salt R 1 3 R 2 PCl. The invention also discloses a method for synthesizing tetrahydrofuran-3-formaldehyde using the composite catalyst. The invention not only overcomes the shortcoming that traditional cobalt-based catalysts must be carried out under high temperature and high pressure, the reaction conditions are mild, but also solves the problem of expensive rhodium carbonyl catalysts.

Description

technical field [0001] The invention relates to the technical field of chemical synthesis, in particular to a composite catalyst for synthesizing tetrahydrofuran-3-carbaldehyde and a method for synthesizing tetrahydrofuran-3-carbaldehyde using the catalyst. Background technique [0002] Olefin hydroformylation is an important way to synthesize organic intermediate aldehydes. With the continuous expansion of the use of tetrahydrofuran-3-carbaldehyde, the significance of 2,5-dihydrofuran hydroformylation to synthesize tetrahydrofuran-3-carbaldehyde is also becoming more and more important. . Catalysts are the key to the hydroformylation technical route. There are mainly two types of cobalt-based catalysts and rhodium-based catalysts. Cobalt-based catalysts have low activity and harsh reaction conditions; although rhodium-based catalysts are expensive, they have high activity and mild reaction conditions. research hotspot. [0003] In 1938, when Otto Roelen was studying the s...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): B01J31/20B01J31/22B01J31/28C07D307/12
CPCC07D307/12B01J27/128B01J31/0239B01J31/0267B01J31/04B01J31/20B01J31/22B01J31/28B01J2231/321B01J2531/842B01J2531/845B01J35/19
Inventor 范立攀范朝辉李合军孙良杨达贾成国
Owner HEBEI VEYONG BIO CHEM