Root canal debridement and disinfection bio-gum bio-material and preparation method thereof

A biomaterial and bioadhesive technology is applied in the fields of biomedicine or medical device dressings to achieve the effects of promoting wound repair and healing, reducing wastage, and reducing exudation

Pending Publication Date: 2018-11-02
JIANGSU HAIERZI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many disadvantages in the use of these root canal irrigation solutions

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] A kind of root canal debridement, disinfection biological colloid solution, each component and mass fraction thereof are:

[0043] Sodium Alginate 1.0%;

[0044] Antimicrobial peptide 100ppm

[0045] Lysozyme 50ppm

[0046] Regulating osmotic pressure substances: sodium chloride 0.9%;

[0047] Water for injection or purified water: enough.

[0048] A preparation method of root canal debridement and disinfection biological colloid solution: prepare according to the following steps:

[0049] Step 1) Dissolve sodium alginate in water for injection or purified water to obtain solution ①, set aside;

[0050] Step 2) Decompose the antimicrobial peptide into water for injection or purified water to obtain a solution ②, set aside;

[0051] Step 3) Dissolve lysozyme in water for injection or purified water to obtain a solution ③, set aside;

[0052] Step 4) Dissolving sodium chloride in water for injection or purified water to obtain a solution ④, set aside;

[0053] Step...

Embodiment 2

[0056] A kind of root canal debridement, disinfection biological colloid solution, each component and mass fraction thereof are:

[0057] Sodium alginate 0.5%;

[0058] Antimicrobial peptide 50ppmppm

[0059] Lysozyme 50ppm0ppm

[0060] Regulating osmotic pressure substances: glycine 1.5%;

[0061] Water for injection or purified water: balance.

[0062]A preparation method of root canal debridement and disinfection biological colloid solution: prepare according to the following steps:

[0063] Step 1) Dissolve sodium alginate in water for injection or purified water to obtain solution ①, set aside;

[0064] Step 2) Decompose the antimicrobial peptide into water for injection or purified water to obtain a solution ②, set aside;

[0065] Step 3) Dissolve lysozyme in water for injection or purified water to obtain a solution ③, set aside;

[0066] Step 4) Dissolving sodium chloride in water for injection or purified water to obtain a solution ④, set aside;

[0067] Step 5...

Embodiment 3

[0070] A kind of root canal debridement, disinfection biological colloid solution, each component and mass fraction thereof are:

[0071] Sodium Alginate 0.4%;

[0072] Antimicrobial peptide 80ppm

[0073] Lysozyme 200ppm

[0074] Substances for adjusting osmotic pressure: sodium chloride 1.0%;

[0075] Water for injection or purified water: balance.

[0076] A preparation method of root canal debridement and disinfection biological colloid solution: prepare according to the following steps:

[0077] Step 1) Dissolve sodium alginate in water for injection or purified water to obtain solution ①, set aside;

[0078] Step 2) Decompose the antimicrobial peptide into water for injection or purified water to obtain a solution ②, set aside;

[0079] Step 3) Dissolve lysozyme in water for injection or purified water to obtain a solution ③, set aside;

[0080] Step 4) Dissolving sodium chloride in water for injection or purified water to obtain a solution ④, set aside;

[0081] ...

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Abstract

The invention discloses a root canal debridement and disinfection bio-gum bio-material applicable to endodontics and a preparation method thereof. Bio-gum solution is prepared with sodium alginate, antimicrobial peptides, lysozyme and injection water as a carrier, in conjunction with sodium chloride that regulates osmotic pressure. The root canal debridement and disinfection bio-gum bio-material belongs to stomatology department and endodontics, is applicable to root canal lubrication, disinfection and washing, and is capable of removing residues at root canal, pulp tissue and other sites by washing, debriding and flushing wounds during oral surgery to promote wound healing, stopping bleeding and reducing exudation, stopping local bleeding of the oral cavity, stopping bleeding after toothextraction, and reducing exudation.

Description

technical field [0001] The invention relates to a root canal debridement and disinfection bio-glue biological material and a preparation method thereof, which is applied to the disinfection, debridement, lubrication and hemostasis biological material of dental endodontics, and belongs to the category of biomedicine or medical device dressings. Background technique [0002] Perfect root canal treatment is the basis for later restoration and long-term preservation of affected teeth. The success of root canal treatment depends on the complete removal of the root canal infection. Because the structure of the oral root canal system is very complex, there are many small root canals and reticular root canals in addition to the root canal. Mechanical preparation is only for the main root canal, and more than 35% of the root canal surface is not involved, and the infection in these parts still exists. After the mechanical preparation of the root canal, a layer of slime will be form...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K6/00A61K38/47A61P7/04A61P31/02A61K31/734A61K38/00
CPCA61K31/734A61K38/00A61K38/47A61P7/04A61P31/02A61K6/52C12Y302/01017A61K2300/00
Inventor 胡军胡静雯胡媛媛
Owner JIANGSU HAIERZI BIOTECH CO LTD
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