Sandwich type composite membrane support

Abstract

The invention provides a sandwich type composite membrane support which comprises a compact outer layer, a sandwich layer and an inner layer, wherein the compact outer layer, the sandwich layer and the inner layer are arranged from top to bottom; the compact outer layer is a polylactic acid membrane, the sandwich layer is prepared from biological active factor loaded mesoporous biological active glass balls, and the inner layer is a seed cell loaded chitosan membrane. Therefore, the problem that a single nerve tract which is damaged (but not died) cannot be repaired and treated by the prior art is solved; the problems that an existing drug carrier system cannot achieve directional medicine release and cannot ensure high concentrations of damaged partial factors are solved; the problems that most drug carrier systems are easy to degrade, the drug carrier amount is low, and medicine release cannot run through a spinal cord injury repairing process all the time are solved; the problems that the drug carrier systems is overlarge in volume, may compress spinal cord and meanwhile are not favorable for sewing endorhachis to cause leakage of cerebrospinal fluid are solved.

Description

technical field [0001] The invention relates to the technical field of medical equipment, in particular to a sandwich type composite membrane support. Background technique [0002] Spinal cord injury (SCI) is the damage of the spinal cord or cauda equina to varying degrees in the spinal canal caused by various reasons. It is mainly caused by traffic injuries and violent injuries. It not only directly causes the loss of movement and working ability and sensory impairment of patients, but also causes the corresponding respiratory, urinary, digestive system and other organ dysfunction due to the damage of the central nervous system below the injury level. [0003] In addition to the extremely weak regeneration of nerve cells, the reasons that affect the recovery of spinal cord function after spinal cord injury include the following aspects, such as: the lack of neurotrophic factors in the injured area, the formation of glial scars, and the formation of oligodendrocytes after ax...

AI Technical Summary

Problems solved by technology

The present invention can solve the problem that a single nerve bundle that has been damaged (but not dead) cannot be repaired and treated by the prior art; the problem that the existing drug-loading system cannot realize the directional release of the drug and cannot guarantee the high concentration of the damaged local factor; Most of the drug-loading systems are easy to degrade, the drug-loading capacity is low, and the drug release cannot run through the whole process of spinal cord injury repair; the drug-loading system is too large, which may compress the spinal cord, and is not conducive to suturing the dura mater, resulting in the formation of cerebrospinal fluid leakage question

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