Traditional Chinese medicine compound prescription for preventing and treating livestock and poultry diarrhea and preparation process of traditional Chinese medicine compound prescription

A technology for livestock and poultry diarrhea and preparation process, which is applied in the field of traditional Chinese veterinary medicine, can solve the problems of large water content of medicinal residues, etc., and achieves the effects of fast disappearance of symptoms, fast effect, and fast effect.

Active Publication Date: 2018-11-09
NANJING AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The extracted medicinal dregs have a large water content and are generally treated as solid waste, which brings certain pressure to environmental protection

Method used

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  • Traditional Chinese medicine compound prescription for preventing and treating livestock and poultry diarrhea and preparation process of traditional Chinese medicine compound prescription
  • Traditional Chinese medicine compound prescription for preventing and treating livestock and poultry diarrhea and preparation process of traditional Chinese medicine compound prescription
  • Traditional Chinese medicine compound prescription for preventing and treating livestock and poultry diarrhea and preparation process of traditional Chinese medicine compound prescription

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Weigh 26 parts of dandelion, 20 parts of Smilax cocos, 26 parts of Viola chinensis, 20 parts of wild chrysanthemum, and 26 parts of Patrinia according to parts by weight, screen and clean; ultrafinely pulverize the above-mentioned raw materials, and pulverize them to 800-1000 mesh; Add sodium hydroxide and water 80 DEG C and soak for 60 minutes, the extraction solvent is drinking water, the solvent used and the raw material ratio are 6: 1, and the sodium hydroxide addition is solvent 1%; Use decanter centrifuge (3000r / min) and Butterfly centrifuge (6000r / mim) for solid-liquid separation; use dilute hydrochloric acid to adjust the pH value of the extract to the range of 3.5-4.0; concentrate the above extract to a density of 1.05-1.10. The concentration method adopts a three-effect concentrator, and the vacuum degree and evaporation temperature of each effect are: the vacuum degree and evaporation temperature of each effect are: the first effect -0.04~-0.07MPa, 85°C; the s...

Embodiment 2

[0023] Weigh 30 parts of dandelion, 24 parts of Smilax cocos, 30 parts of Viola chinensis, 24 parts of wild chrysanthemum, and 30 parts of Patrinia according to parts by weight, screen and clean; ultrafinely pulverize the above-mentioned raw materials, and pulverize them to 800-1000 mesh; Add sodium hydroxide and water 80 DEG C and soak for 60 minutes, the extraction solvent is drinking water, the solvent used and the raw material ratio are 6: 1, and the sodium hydroxide addition is solvent 1%; Use decanter centrifuge (3000r / min) and Butterfly centrifuge (6000r / mim) for solid-liquid separation; use dilute hydrochloric acid to adjust the pH value of the extract to the range of 3.5-4.0; concentrate the above extract to a density of 1.05-1.10. The concentration method adopts a three-effect concentrator, and the vacuum degree and evaporation temperature of each effect are: the vacuum degree and evaporation temperature of each effect are: the first effect -0.04~-0.07MPa, 85°C; the s...

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Abstract

The invention relates to a traditional Chinese medicine compound prescription for preventing and treating livestock and poultry diarrhea and a preparation process of the traditional Chinese medicine compound prescription. The traditional Chinese medicine compound prescription is prepared from the following components in parts by weight: 25 to 30 parts of herba taraxaci, 20 to 25 parts of rhizoma smilacis glabrae, 25 to 30 parts of herba violae, 20 to 25 parts of flos chrysanthemi indici, and 25 to 30 parts of herba patriniae. The preparation method comprises the following steps: measuring theraw materials according to the weight parts, screening, performing superfine freeze smashing on the raw materials, and smashing into powder of 800 to 1000 meshes; adding 1 percent sodium hydroxide andwater, soaking for 60 minutes at 80 DEG C, performing solid-liquid separation by separately using a horizontal spiral centrifugal machine and a butterfly-type centrifugal machine, and adjusting the PH value of an extraction solution by using dilute hydrochloric acid to be 3.5 to 4.0; and concentrating the extract solution by adopting a triple-effect concentrator until the density is 1.05 to 1.10,performing centrifugal filtration, performing spray drying on the concentrated solution to form a water-soluble product or adsorbing by using the particle silicon dioxide, and drying by using a bladespiral drying method to form granular powder. The traditional Chinese medicine compound prescription has the effects of clearing away heat and toxic materials, eliminating the inflammation, and apparently inhibiting the common pathogenic bacteria of pigs and chicken such as escherichia coli, and can substitute the antibiotics to prevent and treat the livestock and poultry diarrhea.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese veterinary medicines, in particular to traditional Chinese medicine prescriptions such as dandelion, smilax smilax, zihuadiding, wild chrysanthemum, Patrinia and the extraction and preparation process. Background technique [0002] Livestock and poultry diarrhea diseases are not only one of the serious problems that plague the farmers in our country, but also one of the main reasons for the loss of animal husbandry in all countries in the world. Antibiotics are the most common way to prevent livestock and poultry diarrhea, but long-term non-standardization and abuse of antibiotics have caused serious drug resistance in pathogens, and drug residues continue to threaten the lives of humans and animals and damage the ecological environment. Therefore, there is an urgent need to study new drugs or technologies to replace antibiotics and reduce their adverse consequences and harms. Traditi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K36/90A61P1/12A61P31/04
CPCA61K36/287A61K36/288A61K36/84A61K36/86A61K36/896A61K36/90A61K2236/331A61K2236/51A61P1/12A61P31/04A61K2300/00
Inventor 王德云朱少武武志勇刘振广胡元亮刘家国
Owner NANJING AGRICULTURAL UNIVERSITY
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