Organic selenium effervescent tablet and preparation method thereof
An effervescent tablet, organic selenium technology, which is applied in the directions of organic active ingredients, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. Poor and other problems, to achieve the effect of uniform composition, good absorption effect and reasonable ratio
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[0052] The present invention provides a kind of preparation method of above-mentioned organic selenium effervescent tablet, comprises the following steps: the mixture of alkaline agent, acid agent, stabilizer, sweetener, chelating agent and L-selenium-methylselenocysteine Tablets are obtained to obtain the organic selenium effervescent tablets.
[0053] In a preferred embodiment of the present invention, the preparation method comprises the following steps:
[0054] (a) uniformly mixing the alkali agent, the sweetener and the stabilizer, wet granulation and drying to obtain the first granule;
[0055] (b) subjecting the acid agent to wet granulation and drying to obtain second granules;
[0056] (c) Mix the chelating agent, L-selenium-methylselenocysteine, the first granule and the second granule evenly, and press into tablets to obtain organic selenium effervescent tablets.
[0057] The method has simple process and convenient operation, and the prepared organic selenium ef...
Embodiment 1
[0073] The present embodiment provides a kind of organic selenium effervescent tablet, comprises by weight: 600 parts of sodium carbonate, 1700 parts of citric acid, 500 parts of sodium citrate, 400 parts of maltitol, 200 parts of sorbitol and L-selenium- 0.25 parts of methyl selenocysteine.
Embodiment 2
[0075] The present embodiment provides a kind of organic selenium effervescent tablet, comprises by weight: 1000 parts of sodium carbonate, 1500 parts of citric acid, 700 parts of sodium citrate, 200 parts of maltitol, 400 parts of sorbitol and L-selenium- 0.01 parts of methyl selenocysteine.
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