Composition with function of adsorbing heavy metal and application of composition

A technology for adsorbing heavy metals and metal chelates, applied in cosmetic preparations, preparations for skin care, cosmetics, etc., can solve the problems of limited and chronic poisoning heavy metal removal ability, achieve good material stability, avoid adverse reactions, use wide range of effects

Inactive Publication Date: 2018-12-11
泉州三欣新材料科技有限公司
View PDF2 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is that, aiming at the problem of chronic poisoning caused by heavy metal pollution of people's skin in current life and the problem of limited ability to remove heavy metals from the surface of human skin in the prior art, the present invention provides a combination with the function of adsorbing heavy metals The composition contains hydrogel microspheres with heavy metal adsorption function, and the hydrogel microspheres have the ability to bind heavy metals on the skin surface, such as heavy metals such as Pb, Cd and Hg

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Composition with function of adsorbing heavy metal and application of composition
  • Composition with function of adsorbing heavy metal and application of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] (1) Preparation of metal chelates

[0037]Dissolve 100g of ethylenediaminetetraacetic acid in 600g of deionized water, add 100g of N-hydroxysuccinimide (NHS) and 200g of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide salt acid salt (EDC), adjust the pH value to 6, and perform an activation reaction at 40°C to obtain an intermediate solution; add 20 g of dopamine to the intermediate solution, adjust the pH value to 3.5, and stir and react at room temperature for 40 hours to obtain a reaction solution; Diethyl ether is added to the reaction solution to generate a precipitate, which is collected by centrifugation and vacuum-dried to obtain a metal chelate;

[0038] (2) Preparation of heavy metal adsorption hydrogel microspheres

[0039] Mix 100g of polyvinyl alcohol hydrogel microspheres, 30g of metal chelates, 200g of ethanol, and 1000g of deionized water, stir evenly, adjust the pH to 8.4, and react at 30°C for 12 hours to obtain a hydrogel reaction liquid; The hydrogel...

Embodiment 2

[0043] (1) Preparation of metal chelates

[0044] Dissolve 100g of diethylenetriaminepentaacetic acid in 1000g of deionized water, add 200g of N-hydroxysuccinimide (NHS) and 100g of 1-(3-dimethylaminopropyl)-3-ethylcarbodi imine hydrochloride (EDC), adjust the pH value to 6, and perform an activation reaction at 30°C to obtain an intermediate solution; add 30g of dopamine to the intermediate solution, adjust the pH value to 4, and stir the reaction at room temperature for 20h to obtain Reaction solution; Add ether to the reaction solution to generate a precipitate, which is collected by centrifugation and vacuum-dried to obtain a metal chelate;

[0045] (2) Preparation of heavy metal adsorption hydrogel microspheres

[0046] Mix 100g of cellulose hydrogel microspheres, 50g of metal chelate, 500g of ethanol, and 2000g of deionized water, stir evenly, adjust the pH to 8, and react at 40°C for 12 hours to obtain a hydrogel reaction liquid; The gel reaction solution is filtered ...

Embodiment 3

[0050] (1) Preparation of metal chelates

[0051] Dissolve 100 g of triethylenetetraminehexaacetic acid in 600 g of deionized water, add 1 g of N-hydroxysuccinimide (NHS) and 1 g of 1-(3-dimethylaminopropyl)-3-ethylcarbodiene Amine hydrochloride (EDC), adjust the pH value to 5, and perform an activation reaction at 20°C to obtain an intermediate solution; add 5g of dopamine to the intermediate solution, adjust the pH value to 7, and stir the reaction at room temperature for 20 hours to obtain the reaction solution; add ether to the reaction solution to generate a precipitate, which is collected by centrifugation and vacuum-dried to obtain a metal chelate;

[0052] (2) Preparation of heavy metal adsorption hydrogel microspheres

[0053] Mix 100g of agarose hydrogel microspheres, 30g of metal chelates, 100g of ethanol, and 1000g of deionized water, stir evenly, adjust the pH to 8.5, and react at 40°C for 3 hours to obtain a hydrogel reaction liquid; The gel reaction solution i...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
particle diameteraaaaaaaaaa
diameteraaaaaaaaaa
particle diameteraaaaaaaaaa
Login to view more

Abstract

The invention discloses a composition with a function of adsorbing heavy metal. The composition contains hydrogel microspheres with the function of adsorbing the heavy metal. The hydrogel microsphereshave the ability of bonding to the heavy metal on the surface of skin. For the hydrogel microspheres with the function of adsorbing the heavy metal, by mainly combining a hydrogel microsphere material with a metal chelating agent and utilizing dopamine as a bridging substance, hydrogel is bonded to the metal chelating agent through a chemical bond; and by utilizing the heavy metal bonding performance of a larger pore structure of the hydrogel and the chelating agent, the hydrogel microsphere material with the function of adsorbing the heavy metal with good heavy metal removal function is obtained. The cosmetic composition adsorbing the heavy metal is quickly and selectively bonded to the surface of the skin and remove the toxic heavy metal on the surface of the skin when be applied to skin-care cosmetics or drugs, has high selectivity, large adsorption capacity and high adsorption rate and avoids the adverse reaction which occurs by orally taking a toxin expelling drug.

Description

technical field [0001] The invention relates to a composition with the function of adsorbing heavy metals and its application, in particular to a heavy metal adsorption composition containing hydrogel microspheres and its application in cosmetics and skin care products. Background technique [0002] With the rapid development of industrialization, heavy metal pollution has become a social concern. Generally speaking, heavy metal pollution refers to the pollution of heavy metal ions such as lead, mercury, cadmium, and arsenic. Due to the random discharge of industrial wastewater, waste gas, and waste residues, as well as the abuse of agricultural pesticides and fertilizers, a large number of toxic heavy metal ions pollute through water, air, soil, and biological chains to animal and plant products and water sources that human beings rely on for survival. cause potential harm. In addition, in daily life, some daily necessities (glasses, cosmetics, clothing, toys, etc.), mobi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/34A61K8/36A61K8/41A61K8/44A61K8/73A61K8/86A61K8/92A61Q19/00
CPCA61K8/345A61K8/361A61K8/41A61K8/44A61K8/73A61K8/735A61K8/86A61K8/92A61K8/922A61K8/925A61Q19/00
Inventor 彭新艳刘云鸿刘云晖
Owner 泉州三欣新材料科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap