Monascus purpureus strain, and fermentation product thereof and fermentation method thereof

A technique of Monascus violaceum and a fermentation method, applied in the field of fermentation, can solve the problems of adverse effects of production and utilization, difficult production cost, low efficiency, etc., and achieves the effects of low synthesis amount of citrinin, low cost and simple operation
CN109022293AActive Publication Date: 2018-12-18BEIJING BEINONG HONGZE BIOTECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
BEIJING BEINONG HONGZE BIOTECH CO LTD
Publication Date
2018-12-18

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Abstract

The invention relates to a Monascus purpureus strain, and a fermentation product and a fermentation method thereof. The Monascus purpureus has a strain number of ZX26 and an accession number of CGMCCNO. 15992, and has the advantages of high lovastatin yield, low citrinin synthesis amount, compliance with food safety standards and good genetic stability. The fermentation product comprises myceliaproduced by fermentation and a fermented product lovastatin, and has the advantages of high lovastatin content, low citrinin content, compliance with food safety standards and high nutritional and health-care value. The method comprises a step of inoculating the seed solution of the Monascus purpureus strain into a fermentation medium for oscillating fermentation culture. The fermentation method is simple in operation, low in cost, and convenient for large-scale production. Furthermore, after the fermentation method is optimized, the ability of the Monascus purpureus strain in producing lovastatin can be greatly enhanced.
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Description

technical field

[0001] The invention relates to the field of fermentation, in particular to a strain of Monascus purpura and its fermentation product and fermentation method. Background technique

[0002] Lovastatin is a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, which is a comprehensive lipid-lowering drug, which can competitively inhibit the endogenous cholesterol synthesis rate-limiting enzyme HMG-CoA Reductase, blocking intracellular valonate metabolic pathway, reducing intracellular cholesterol synthesis, thereby stimulating the increase in the number and activity of low-density lipoprotein (LDL) receptors on the cell membrane surface in a feedback manner, increasing serum cholesterol clearance and lowering the level Clinical It is mainly used to lower cholesterol, especially low-density lipoprotein-cholesterol (LDL-C). Due to its advantages of safe use, significant curative effect, and less adverse reactions in the prevention and treatment of...

Claims

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