System and method for ear-arranged transcutaneous vagus nerve stimulation

Abstract

A transcutaneous nerve stimulation system includes a multifunctional earphone assembly that receives a sound signal from a sound source or other sources (such as a signal generator). An amplifier receiving the sound signal from the sound source or independent signal generator amplifies the sound signal to generate an amplified electrical signal. A stimulator, which includes multiple conductive electrode contacts, is coupled to the amplifier to receive the amplified electrical signal. The electrode contacts may protrude from an earbud / headphone or extend from an adjustable probe arm. The amplified electrical signal is used to apply electrical stimulation while the earphone assembly emits audible sounds according to the sound signal. The combined functionality enhances compliance with treatment regimens involving electrical stimulation of vagus nerves and other regions of a subject. Potential indications include, without limitation, major depressive disorder, epilepsy, chronic pain, pre-diabetes, insomnia, cardiovascular disorders, tinnitus, autism, daily stress, and anxiety.

Description

[0001] Cross References to Related Applications [0002] This application is related to US Application Serial No. 62 / 258,684, entitled "Combined Earplugs and Transcutaneous Vagus Nerve Stimulation," filed November 23, 2015 and is incorporated herein by reference in its entirety. technical field [0003] This document relates to an invention generally related to sound transmission and peripheral nerve modulation of the pinna using a multifunctional earphone (headphone / earphone) assembly. Background technique [0004] The vagus nerve is the longest cranial nerve that travels from the medulla in the brain to the colon. The vagus nerve innervates the thoracic and abdominal organs and supplies motor parasympathetic fibers to all organs except the adrenal glands. The vagus nerve is involved in the autonomic, cardiovascular, respiratory, gastrointestinal, immune, and endocrine systems, and it helps regulate heart rate, blood pressure, vascular resistance, airway diameter, breathin...

AI Technical Summary

Problems solved by technology

However, stimulating the ear canal can have side effects, such as hearing loss, and vagal physiological responses, such as dizziness and throat discomfort

Also, user privacy / confidentiality may not be fully protected

Additionally, the user must acquire an integrated device which is limited in its ability to deliver different stimulation modes / frequency / waveforms

The device is also limited in its ability to ensure the highest quality sound

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