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A traditional Chinese medicine for the treatment of syndrome of stagnation of deficiency and blood stasis after comprehensive minimally invasive surgery for primary liver cancer

A technology for primary liver cancer and stasis due to deficiency, applied in the field of medicine, can solve the problems of aggravated adverse reactions, poor liver function, lack of prevention and treatment measures, etc., and achieves the effects of scientific and reasonable compatibility, convenient taking, and rich raw materials.

Active Publication Date: 2021-06-29
THE FIRST AFFILIATED HOSPITAL OF HENAN UNIV OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Patients with liver cancer often have liver cirrhosis of varying degrees and poor liver function. The Guidelines for the Diagnosis and Treatment of Primary Liver Cancer include transcatheter arterial chemoembolization (TACE) and local ablation (comprehensive minimally invasive) in the treatment of liver cancer. Various treatment methods The combination can improve the survival rate and treatment effect of liver cancer patients, and can effectively reduce the mortality rate of liver cancer patients. However, many patients have postoperative syndrome after comprehensive minimally invasive surgery, mainly manifested as fever, right upper quadrant pain, loss of appetite, nausea and vomiting , fatigue, liver function damage, kidney damage in severe cases, etc., seriously affecting the quality of life of patients, the postoperative disease control rate is still not ideal, and there is a lack of effective prevention and treatment measures
Although radiotherapy, chemotherapy and targeted therapy can delay the progression of the disease to a certain extent, the adverse reactions are aggravated. Traditional Chinese medicine can adjust the stability of the body's internal environment through overall adjustment and syndrome differentiation, enhance the body's resistance to disease, relieve symptoms, improve the quality of life, and prolong the life of the patient. Survival period can normalize the body's morbid state, thereby improving the body's tolerance to minimally invasive treatment. Therefore, it is imperative to invent a Chinese medicine for the treatment of primary liver cancer comprehensive minimally invasive postoperative syndrome

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0008] When the present invention is implemented, it can be made from the following raw materials by weight: Astragalus 26g, Smilax 34g, Codonopsis 13g, Atractylodes macrocephala 17g, Radix Paeoniae Alba 13g, Salvia miltiorrhiza 34g, turtle shell 17g, oyster 34g, cat ginseng 26g, tangerine peel 13g , Radix Bupleurum 9g and Radix Glycyrrhizae 7g, wherein, Atractylodes Rhizoma Atractylodes Rhizome, dried tangerine peel are pulverized, the mass concentration that adds Atractylodes Rhizoma Atractylodes Rhizome and dried tangerine peel 5 times is percolated with 70% ethanol, under 50 ℃ condition, under reduced pressure concentration, preparation is that the relative density is 1.2 For the extract, combine the dregs obtained from the above two medicinal materials with 10 medicinal materials of astragalus, smilax, codonopsis, white peony root, salvia miltiorrhiza, turtle shell, oyster, cat ginseng, Bupleurum, and licorice, and add 4 times the amount of the raw drug Decocting in water ...

Embodiment 2

[0010] When the present invention is implemented, it can also be made from the following raw materials by weight: Astragalus 30g, Smilax 30g, Codonopsis 15g, Atractylodes macrocephala 15g, Radix Paeoniae Alba 15g, Salvia miltiorrhiza 30g, turtle shell 20g, oyster 30g, cat ginseng 30g, tangerine peel 12g, Bupleurum 10g and licorice 6g, among them, Atractylodes macrocephala and tangerine peel were crushed, and 5 times the amount of Atractylodes macrocephala and tangerine peel were percolated with 70% ethanol, and concentrated under reduced pressure at 50°C to prepare a relative density of 1.2 For the extract, combine the dregs obtained from the above two medicinal materials with 10 medicinal materials such as Astragalus, Smilax, Codonopsis Radix, Radix Paeoniae Alba, Salvia Miltiorrhiza, Turtle Shell, Oyster, Cat Ginseng, Bupleurum, and Licorice, and add 5 times the raw drug The amount of water was decocted twice, each time for 2 hours, and the decoctions obtained in the two time...

Embodiment 3

[0012] When the present invention is implemented, it can also be made from the following raw materials by weight: Astragalus 34g, Smilax 26g, Codonopsis 17g, Atractylodes macrocephala 13g, Radix Paeoniae Alba 17g, Salvia miltiorrhiza 26g, turtle shell 23g, oyster 26g, cat ginseng 34g, tangerine peel 11g, Bupleurum 11g and licorice 5g, among them, Atractylodes macrocephala and tangerine peel were crushed, and 5 times the amount of Atractylodes macrocephala and tangerine peel were percolated with 70% ethanol, and concentrated under reduced pressure at 50°C to prepare a relative density of 1.2 For the extract, the dregs obtained from the above two medicinal materials are combined with 10 medicinal materials such as Astragalus, Smilax, Codonopsis Radix, Radix Paeoniae Alba, Salvia Miltiorrhiza, Turtle Shell, Oyster, Cat Ginseng, Bupleurum, and Licorice, and the raw drug is added 6 times The amount of water was decocted twice, each time for 2 hours, and the decoctions obtained in th...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine for the treatment of stagnation of deficiency and blood stasis syndrome after comprehensive minimally invasive surgery of primary liver cancer, which can effectively solve the medication problem of stagnation of deficiency and stagnation syndrome after comprehensive minimally invasive surgery of primary liver cancer. The technical solution is as follows: Traditional Chinese medicine is made from the following raw materials by weight: Astragalus 25‑35g, Smilax 25‑35g, Codonopsis 12‑18g, Atractylodes macrocephala 12‑18g, Radix Paeoniae Alba 12‑18g, Salvia miltiorrhiza 25‑35g, turtle shell 16‑24g, 25-35g of oysters, 25-35g of cat ginseng, 10-14g of tangerine peel, 8-12g of Bupleurum and 5-7g of licorice, the present invention has scientific and reasonable compatibility, rich raw materials, convenient taking, good effect, and has the effect of strengthening the body and eliminating pathogens. It is effectively used in the treatment of patients with syndrome of stagnation of deficiency and stagnation after comprehensive minimally invasive surgery of primary liver cancer, and it is an innovation in the treatment of syndrome of stagnation of stagnation of deficiency and stagnation after comprehensive minimally invasive surgery of primary liver cancer.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine for treating syndrome of deficiency and blood stasis after comprehensive minimally invasive surgery for primary liver cancer. Background technique [0002] Primary liver cancer is one of the most common malignant tumors in my country. Its incidence rate is the fifth among malignant tumors and the third cause of cancer-related deaths. Its five-year natural case fatality rate is greater than 95%. Patients with liver cancer often have liver cirrhosis of varying degrees and poor liver function. The Guidelines for the Diagnosis and Treatment of Primary Liver Cancer include transcatheter arterial chemoembolization (TACE) and local ablation (comprehensive minimally invasive) in the treatment of liver cancer. Various treatment methods The combination can improve the survival rate and treatment effect of liver cancer patients, and can effectively reduce the mortality...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/90A61K36/896A61P35/00A61K35/586A61K35/618
CPCA61K35/586A61K35/618A61K36/185A61K36/233A61K36/284A61K36/344A61K36/481A61K36/484A61K36/537A61K36/65A61K36/71A61K36/752A61K36/896A61K36/90A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61P35/00A61K2300/00
Inventor 陈欣菊马素平陈晓琦冀爱英郝尧坤
Owner THE FIRST AFFILIATED HOSPITAL OF HENAN UNIV OF TCM