Chinese medicine composition for preventing chemotherapy-induced premature ovarian failure and preparation method and application thereof

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a Chinese medicine composition for preventing chemotherapy-induced premature ovarian failure, a preparation method and application thereof. The Chinese medicine composition of the invention includes 100-300 parts of raspberry, 200-500 parts of radix pseudostellariae, 150-450 parts of fructuspsoraleae, 200-500 parts of glossy privet fruits, 150-450 parts of radix salviae miltiorrhizae, 100-300 parts of fried jujube kernel, and 100-300 parts of herba epimedii; and the Chinese medicine composition is prepared by the steps of alcohol extraction, vacuum concentration, spray drying, etc. The Chinese medicine composition of the invention has reasonable composition ratio, and exact clinicalcurative effects, can effectively prevent chemotherapy-induced premature ovarian failure, and remarkably improve the quality of life of patients, has no toxic and side effects, is safe to take, has less medicinal flavor, is easy in control quality, and has low cost.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for preventing chemotherapy-induced premature ovarian failure, a preparation method and application thereof. Background technique [0002] With the development of modern medicine, chemotherapy has become the main anti-tumor treatment method, and the survival rate of malignant tumor patients after treatment has been significantly improved. However, the ovary is very sensitive to chemotherapy drugs, and chemotherapy can easily lead to premature ovarian failure. 68% of adult female patients will experience one or more symptoms of ovarian function damage after undergoing cancer chemotherapy, and premature ovarian failure menopause symptoms caused by chemotherapy More severe than physiological menopausal symptoms. Therefore, although chemotherapy drugs prolong the survival of patients to a certain extent, the...

AI Technical Summary

Problems solved by technology

However, the ovary is very sensitive to chemotherapy drugs, and chemotherapy can easily lead to premature ovarian failure. 68% of adult female patients will experience one or more symptoms of ovarian function damage after undergoing cancer chemotherapy, and premature ovarian failure menopause symptoms caused by chemotherapy More severe than physiological menopausal symptoms

Therefore, although chemotherapy drugs prolong the survival of patients to a certain extent, they seriously affect the quality of life of female patients, especially for young women.

[0003] At present, in clinical practice, drugs such as goserelin are used before chemotherapy to reduce the incidence of premature ovarian failure. However, the actual therapeutic effect is related to various factors such as chemotherapy regimen and patient age. Make the ovaries in a dependent state, which may lead to poorer ovarian function

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