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Preparation technology capable of improving difference of filling amount of bovine colostrum freeze-dried powder capsules

A technology for preparation process and difference in filling capacity, which is applied in the field of preparation process for improving the difference in filling capacity of bovine colostrum freeze-dried powder capsules, can solve problems such as inconsistencies, and achieve the effects of promoting healing, rapid and complete absorption, and delaying aging

Inactive Publication Date: 2019-02-15
康道生物(南通)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In the prior art, the freeze-dried bovine colostrum powder passes through an 8-mesh sieve. When the capsule is filled, it is detected according to the requirements for the difference in the filling volume under the item "0103 Capsule" in the fourth part of the Chinese Pharmacopoeia 2015 edition. The capsule loading of the bovine colostrum freeze-dried powder The difference is between -13.5% - +17.8%, which does not meet the specified requirements of ±10%

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0020] Preparation technique of the present invention comprises the following steps:

[0021] A. Pass the lyophilized colostrum powder through a 10-mesh standard sieve, then carry out a filling test on the lyophilized colostrum powder after sieving, and obtain test data A;

[0022] B. Pass the lyophilized colostrum powder through a 12-mesh standard sieve, then carry out a filling test on the lyophilized colostrum powder after sieving, and obtain test data B;

[0023] C. Pass the freeze-dried colostrum powder through a 16-mesh standard sieve, and then carry out a filling test on the sieved freeze-dried colostrum powder to obtain test data C;

[0024] D. Pass the lyophilized colostrum powder through a 18-mesh standard sieve, then carry out a filling test on the lyophilized colostrum powder after sieving, and obtain test data D;

[0025] E. Pass the lyophilized colostrum powder through a 20-mesh standard sieve, then carry out a filling test on the lyophilized colostrum powder af...

experiment example

[0030] Use each standard sieve to sieve and fill, then test, the data obtained are as follows:

[0031] Pass 10 mesh sieve

Loading difference (%)

Pass 12 mesh sieve

3.8

Pass 16 mesh sieve

3.2

Pass 18 mesh sieve

1.1

Pass 20 mesh sieve

2.5

Pass 40 mesh sieve

-2.5

Pass 60 mesh sieve

-1.8

[0032] The present invention finally confirms that the freeze-dried bovine colostrum powder passes through the 18-mesh sieve, the capsule filling operation is smooth, and the loading capacity is stable. The difference in powder loading is between -3.1% and +4.6%, which fully meets the requirements of the Chinese Pharmacopoeia and ensures product quality.

[0033] In summary, the production process of the present invention is advanced and simple, and the microparticle form makes it absorb quickly and completely, and fully exerts its immune regulation, regulates intestinal flora, promotes the growth and development of t...

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Abstract

The invention discloses a preparation technology capable of improving the difference of the filling amount of bovine colostrum freeze-dried powder capsules. Each capsule is filled with content including 190-210 mg of bovine colostrum freeze-dried powder. The production technology is advanced and simple, due to the small particle form, the capsules are quickly and completely absorbed, the functionsare given full play to that the immunity is adjusted, the intestinal flora is adjusted, growth and development of the gastrointestinal tract are promoted or healing of intestinal tissue wound is promoted, senescence is delayed, and growth and development are promoted, and the bovine colostrum freeze-dried powder capsules are suitable for various sub-healthy and postoperative crowds. The functionsof active immunoglobulins in the bovine colostrum freeze-dried powder can be effectively ensured, the functions are added that the immunity is adjusted, the intestinal flora is adjusted, growth and development of the gastrointestinal tract are promoted or healing of intestinal tissue wound is promoted, senescence is delayed, and growth and development are promoted, and the health-care effects ofthe product are greatly improved.

Description

technical field [0001] The invention relates to the technical field of preparation of bovine colostrum freeze-dried powder capsules, in particular to a preparation process for improving the difference in filling capacity of bovine colostrum freeze-dried powder capsules. Background technique [0002] Bovine colostrum is the milk of cows within 3 days after calving. Compared with ordinary milk, its nutritional content is higher in protein, but lower in fat and sugar. Bovine colostrum also contains a large number of immune and growth factors, such as immunoglobulin, lactoferrin, lysozyme, insulin-like growth factor, epidermal growth factor, etc., and is known as "the health food of the 21st century". The color of bovine colostrum is yellow, thick, fishy smell, high acidity, poor taste, and its composition is quite complex, human beings are not suitable for direct consumption (and direct drinking is likely to ingest bad microorganisms), only after special treatment It can only ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61J3/07A23C9/20
CPCA23C9/206A61J3/074
Inventor 王勇
Owner 康道生物(南通)有限公司
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