A filtration system that prevents cell rupture

A filtration system and cell technology, applied in the field of filtration systems to prevent cell rupture, can solve the problem of not considering whether cells rupture, etc., and achieve the effects of easy automatic control, convenient operation, and prevention of contamination of samples
CN109385369BActive Publication Date: 2021-10-08THE SECOND XIANGYA HOSPITAL OF CENT SOUTH UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
THE SECOND XIANGYA HOSPITAL OF CENT SOUTH UNIV
Publication Date
2021-10-08

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Abstract

The invention provides a filter system capable of preventing cell rupture, comprising a filter, a sample inlet tube, a liquid outlet tube, a bubble monitor, a valve and a control component, wherein a filter membrane is arranged in the filter; the sample inlet tube communicates with the filter; The liquid outlet pipe communicates with the filter; the bubble monitor is arranged on the sampling pipe; the valve is arranged on the liquid outlet pipe; both the air bubble monitor and the valve are connected with the control part. Applying the filtration system of the present invention, the effect is: the overall structure is simplified; through the combined design of the bubble monitor, the valve and the control part, the control part can control the switch of the valve according to the monitoring result of the bubble monitor, and automatically control the filtration process. The termination point ensures that the living cells trapped on the filter membrane are not directly in contact with the air, so that the trapped living cells remain active, which is convenient for the next step of research and analysis.
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Description

technical field

[0001] The invention relates to the technical field of filtration, in particular to a filtration system capable of preventing cell rupture. Background technique

[0002] In the scientific research practice in the field of biomedicine, it is found that the fragmentation of the cell membrane is very easy to occur when the specific living cells are captured and filtered, resulting in the destruction of the entire cell, which has a great impact on further analysis after filtration: on the one hand, after the cell ruptures, the cells The outflow of internal fluid leads to cell death and the inability of cells to maintain activity, resulting in extremely low efficiency of filtering and separating living cells; This immunoassay and analysis has had significant adverse effects.

[0003] Cell filtration systems in the prior art include:

[0004] The utility model patent with the application number 201620130701.1 provides a filter system for filtering out rare circul...

Claims

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