A kind of silver-containing medical hydrocolloid dressing and preparation method thereof
A technology of hydrocolloid and hydrocolloid layer is applied in the field of medical and health auxiliary materials, which can solve the problems of affecting the use effect of hydrocolloid, uneven absorption and exudation of hydrocolloid, uneven bacteriostatic performance, agglomeration and uneven dispersion of hydrophilic microspheres, etc. , to achieve long-term bacteriostatic efficacy, increase compatibility and thermal stability, and good compatibility
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[0046] It should be briefly explained that the main innovation of this application is the introduction of α-cyclodextrin polyrotaxane / silver sulfadiazine as a bacteriostatic agent, and at the same time, related components have been optimized. Therefore, the following examples are mainly based on the optimized composition It is divided into examples to verify the final hydrocolloid dressing and other properties. The relevant experimental conditions are briefly introduced as follows.
[0047] It should be noted that the antibacterial agent α-cyclodextrin polyrotaxane / silver sulfadiazine in the following examples (which can also be prepared with reference to other prior art) was prepared by the inventor according to the following steps:
[0048] (1) Preparation of α-cyclodextrin polyrotaxane
[0049] Take 1.5g of terminal carboxylated polyethylene glycol, put it into a round-bottomed flask, add 25ml of deionized water and stir to dissolve, then add a saturated solution of α-cyclo...
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