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A kind of silver-containing medical hydrocolloid dressing and preparation method thereof

A technology of hydrocolloid and hydrocolloid layer is applied in the field of medical and health auxiliary materials, which can solve the problems of affecting the use effect of hydrocolloid, uneven absorption and exudation of hydrocolloid, uneven bacteriostatic performance, agglomeration and uneven dispersion of hydrophilic microspheres, etc. , to achieve long-term bacteriostatic efficacy, increase compatibility and thermal stability, and good compatibility

Active Publication Date: 2021-06-22
HENAN HUIBO MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the silver-loaded microspheres prepared by this patent, the external carrier is a hydrophilic substance, while the hydrocolloid dressing matrix styrene-isoprene-styrene block copolymer is a hydrophobic substance, and there are hydrophilic substances in the preparation process. Agglomeration and uneven dispersion of water microspheres in the hydrophobic matrix, resulting in uneven absorption of exudate and antibacterial properties of the hydrocolloid, which in turn affects the actual use of the hydrocolloid

Method used

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  • A kind of silver-containing medical hydrocolloid dressing and preparation method thereof
  • A kind of silver-containing medical hydrocolloid dressing and preparation method thereof

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Effect test

Embodiment

[0046] It should be briefly explained that the main innovation of this application is the introduction of α-cyclodextrin polyrotaxane / silver sulfadiazine as a bacteriostatic agent, and at the same time, related components have been optimized. Therefore, the following examples are mainly based on the optimized composition It is divided into examples to verify the final hydrocolloid dressing and other properties. The relevant experimental conditions are briefly introduced as follows.

[0047] It should be noted that the antibacterial agent α-cyclodextrin polyrotaxane / silver sulfadiazine in the following examples (which can also be prepared with reference to other prior art) was prepared by the inventor according to the following steps:

[0048] (1) Preparation of α-cyclodextrin polyrotaxane

[0049] Take 1.5g of terminal carboxylated polyethylene glycol, put it into a round-bottomed flask, add 25ml of deionized water and stir to dissolve, then add a saturated solution of α-cyclo...

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Abstract

This application belongs to the technical field of medical and health auxiliary materials, and specifically relates to a patent application for a silver-containing medical hydrocolloid dressing and a preparation method thereof. The components of the hydrocolloid dressing include: CMC / PEG / PAA particles, thermoplastic rubber, liquid paraffin, tackifying resin, plasticizer, antibacterial agent α-cyclodextrin polyrotaxane / silver sulfadiazine and the like. In general, the application has prepared a hydrocolloid dressing that is safe and non-irritating, has uniform liquid absorption, uniform dispersion of bacteriostatic agents, excellent bacteriostatic performance and long-lasting bacteriostasis through optimization and adjustment of related components, and The dressing has good waterproof and antibacterial properties, absorbs wound exudate and toxic substances in a large amount, can maintain a moist wound healing environment for a long time, and has excellent properties such as non-adhesive wounds, so it has good practical value for wound repair and wound healing.

Description

technical field [0001] This application belongs to the technical field of medical and health auxiliary materials, and specifically relates to a patent application for a silver-containing medical hydrocolloid dressing and a preparation method thereof. Background technique [0002] The skin is the largest organ of the human body. It has important functions such as resisting the invasion of external microorganisms, excreting and preventing water evaporation, regulating body temperature, and maintaining the stability of the internal environment of the body. To avoid further deterioration, functional band-aids are the most commonly used wound aids. [0003] In the prior art, new water-based dressings have developed rapidly in recent years because of their advantages such as convenient use, no limitation of wound size, and strong functionality. Aqueous dressings can directly adhere to wounds because they contain certain viscous components, so they have good application prospects ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L26/00A61L15/26A61L15/30A61L15/42A61L15/44A61L15/46
CPCA61L15/26A61L15/30A61L15/42A61L15/44A61L15/46A61L26/0004A61L26/0009A61L26/0014A61L26/0019A61L26/0023A61L26/0066A61L26/008A61L2300/216A61L2300/232A61L2300/622C08L9/00
Inventor 曹晶晶周新钦杨帅袁召张建鑫王川
Owner HENAN HUIBO MEDICAL CO LTD
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