Silver-containing medical hydrocolloid dressing and preparation method thereof

A hydrocolloid and medical technology, applied in the field of medical and health auxiliary materials, can solve the problems of affecting the use effect of hydrocolloids, uneven absorption and exudation and bacteriostatic properties of hydrocolloids, agglomeration and uneven dispersion of hydrophilic microspheres, etc. Improve and enhance antibacterial properties, increase compatibility and thermal stability, good compatibility

Active Publication Date: 2019-03-01
HENAN HUIBO MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, in the silver-loaded microspheres prepared by this patent, the external carrier is a hydrophilic substance, while the hydrocolloid dressing matrix styrene-isoprene-styrene block copolymer is a hydrophobic substance, and there are hydrophilic substances in the preparation process. Agglomeration and uneven dispersion of water microspheres in the hydrophobic matrix, resulting in uneven absorption of exudate and antibacterial properties of the hydrocolloid, which in turn affects the actual use of the hydrocolloid

Method used

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  • Silver-containing medical hydrocolloid dressing and preparation method thereof
  • Silver-containing medical hydrocolloid dressing and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment

[0046] It should be briefly explained that the main innovation of this application is the introduction of α-cyclodextrin polyrotaxane / silver sulfadiazine as a bacteriostatic agent, and at the same time, related components have been optimized. Therefore, the following examples are mainly based on the optimized composition It is divided into examples to verify the final hydrocolloid dressing and other properties. The relevant experimental conditions are briefly introduced as follows.

[0047] It should be noted that the antibacterial agent α-cyclodextrin polyrotaxane / silver sulfadiazine in the following examples (which can also be prepared with reference to other prior art) was prepared by the inventor according to the following steps:

[0048] (1) Preparation of α-cyclodextrin polyrotaxane

[0049] Take 1.5g of terminal carboxylated polyethylene glycol, put it into a round-bottomed flask, add 25ml of deionized water and stir to dissolve, then add a saturated solution of α-cyclo...

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Abstract

The invention belongs to the technical field of medical and sanitary auxiliary materials and particularly relates to a silver-containing medical hydrocolloid dressing and a preparation method thereof.The hydrocolloid dressing includes CMC/PEG/PAA particles, thermoplastic rubber, liquid paraffin, tackifying resin, a plasticizer, alpha-cyclodextrin polyrotaxane/silver sulfadiazine serving as an antibacterial agent and the like. In general, by optimizing and adjusting relevant components, the hydrocolloid dressing which is safe, free of irritation, uniform in liquid absorption, excellent in antibacterial performance and lasting in antibacterial effect is prepared, and the antibacterial agent is uniformly dispersed. The dressing is great in waterproof and antibacterial performance and capableof absorbing a large amount of exudate and toxic substances of a wound and maintaining a wet healing environment for the wound for a long time without being bonded to the wound and has other excellent performance. Therefore, the dressing has a high practical value for wound repairing and wound healing.

Description

technical field [0001] This application belongs to the technical field of medical and health auxiliary materials, and specifically relates to a patent application for a silver-containing medical hydrocolloid dressing and a preparation method thereof. Background technique [0002] The skin is the largest organ of the human body. It has important functions such as resisting the invasion of external microorganisms, excreting and preventing water evaporation, regulating body temperature, and maintaining the stability of the internal environment of the body. To avoid further deterioration, functional band-aids are the most commonly used wound aids. [0003] In the prior art, new water-based dressings have developed rapidly in recent years because of their advantages such as convenient use, no limitation of wound size, and strong functionality. Aqueous dressings can directly adhere to wounds because they contain certain viscous components, so they have good application prospects ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00A61L15/26A61L15/30A61L15/42A61L15/44A61L15/46
CPCA61L15/26A61L15/30A61L15/42A61L15/44A61L15/46A61L26/0004A61L26/0009A61L26/0014A61L26/0019A61L26/0023A61L26/0066A61L26/008A61L2300/216A61L2300/232A61L2300/622C08L9/00
Inventor 曹晶晶周新钦杨帅袁召张建鑫王川
Owner HENAN HUIBO MEDICAL CO LTD
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