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Adjuvant for coccidian vaccine spray dripping immunization and application thereof

A vaccine and coccidia technology, which can be used in vaccines, veterinary vaccines, aerosol delivery, etc., can solve the problems that chicks cannot obtain effective immunity, the droplets are small, and the water is easy to evaporate.

Inactive Publication Date: 2019-03-08
FOSHAN STANDARD BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, spray immunization is only to dilute the vaccine with water and then spray it. The sprayed droplets are small, and the water attached to the feathers is easy to evaporate, resulting in some chicks unable to obtain effective immunity.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Take 2.5g of guar gum, 0.5g of chitosan oligosaccharide, 0.375g of dried powder, 0.375g of food coloring, 21.25g of anhydrous glucose, mix them evenly, put them into a beaker with 500mL coccidian vaccine diluent, stir evenly, A viscous solution 1 was obtained.

Embodiment 2

[0047] Take 4g of guar gum, 3.4g of chitosan oligosaccharide, 0.6g of blow-dried powder, 1g of food coloring, 11g of anhydrous glucose, mix them evenly, and put them into a beaker with 500mL of coccidiosis vaccine diluent, and stir evenly to obtain a viscous Sexual solution 2.

Embodiment 3

[0049] Take 3.6g of guar gum, 4.5g of chitosan oligosaccharide, 0.75g of dried powder, 0.9g of food coloring, and 5.25g of anhydrous glucose, mix them evenly, and put them into a beaker with 500mL coccidian vaccine diluent, stir evenly, A viscous solution 3 was obtained.

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PUM

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Abstract

The invention discloses an adjuvant for coccidian vaccine spray dripping immunization and application thereof. The adjuvant is prepared from the following ingredients in parts by weight: 10 to 34 parts of guar gum, 2 to 34 parts of chitosan oligosaccharide, 1.5 to 10 parts of dry blowing powder, 1.5 to 7 parts of edible pigments and 15 to 85 parts of anhydrous dextrose. The adjuvant can be fast dissolved into a vaccine diluent at normal temperature, so that the dispersion of the coccidian vaccine is uniform; the moisture can be maintained for a long time; the use is convenient; the adjuvant ismixed into the coccidian vaccine diluent to be directly sprayed onto chickens through the spray dripping equipment; the adjuvant is applicable to intensive chicken farms and large-size hatcheries, sothat chicks fast build the immunity.

Description

technical field [0001] The invention relates to the technical field of biological immunity, in particular to an adjuvant for coccidia vaccine drop immunization and application thereof. Background technique [0002] Chicken coccidiosis is a kind of extremely serious global parasitic disease. One or more Eimeria species of Apicomplexa Eimeria are parasitic in the intestinal mucosal epithelium of chickens, causing diarrhea, Bloody feces, growth retardation, etc. affect the production and development of chickens and even die, causing huge economic losses to the chicken industry every year. At present, anticoccidiosis mainly relies on adding anticoccidial drugs to feed or drinking water. However, due to the increasingly serious problem of coccidiosis drug resistance, and the safety and effectiveness of marketed coccidiosis vaccines have gradually been recognized by the market, the use of coccidia vaccines to prevent chicken coccidiosis has become a new trend. Coccidian vaccine ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/12A61K47/26A61K47/36A61K39/39A61K39/012A61P33/02
CPCA61K9/0014A61K9/12A61K39/012A61K39/39A61K47/26A61K47/36A61K2039/54A61K2039/552A61K2039/55511A61K2039/55583A61P33/02
Inventor 曾莉刘丽丹谭志坚翁亚彪
Owner FOSHAN STANDARD BIO TECH
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