Full-automatic spermatid detector

Abstract

The invention discloses a full-automatic spermatid detector. A seminal fluid sample enters a liquid flow system after being subjected to sample suction, reagent adding and mixed reaction dyeing, the liquid flow system is used for conveying the seminal fluid sample subjected to reaction dyeing to a reaction detection chamber, the seminal fluid sample is subjected to excitation detection by a laseremitted from a laser optical system, a light signal obtained after excitation is collected by a photoelectric detecting system, statistic analysis of data is carried out after the light signal is converted to a digital signal by a control system, and according to data features and a cluster analysis algorithm, semen quality parameter results such as the total quantity of semen, density, core wholeness, mitochondrion membrane potential and acrosomal reaction of the to-be-detected seminal fluid sample are worked out. Full-automatic high-flux rapid detection and analysis of the seminal fluid sample are achieved, full-automatic operation can be carried out after a user places the seminal fluid sample in a sample pond, detection and analysis results are automatically output, the full-automaticspermatid detector can be directly connected to a Lis/His system of a hospital to achieve seamless connection of data management, and the full-automatic spermatid detector is easy and convenient to operate, capable of achieving one-key intelligence, low in cost and wide in adaptability.

Description

technical field [0001] The invention relates to the technical field of novel medical grade clinical detection, in particular to an automatic sperm cell detector. Background technique [0002] Sperm quality evaluation is the core key to diagnosing male (male) fertility. The testing items include sperm density, motility rate, deformity rate, nuclear integrity, mitochondrial membrane potential, acrosome reaction and other sperm individual or group indicators. At present, the main detection equipment includes microscope, fluorescence microscope, general-purpose flow cytometer, etc. The main detection methods include microscope manual inspection, computer-aided sperm analysis system (CASA) assisted analysis, and computer-assisted cell analysis system of flow cytometer. Auxiliary manual analysis. [0003] Manual microscopic examination with a microscope is currently the most mainstream application technology. It mainly uses a microscope to perform counting, viability resolution, ...

AI Technical Summary

Problems solved by technology

[0006] At present, there is a lack of fully automatic, integrated, high-throughput, and low-cost testing instruments for sperm cell-specific analysis in clinical semen testing at home and abroad. The sample processing, instrument testing, and result analysis brought by existing instruments must be carried out separately and require Manual operation, which brings complicated detection operations, cumbersome manual sample processing steps, requires special training for equipment maintenance and operation problems

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