Particle mobility mass spectrometer and particle analysis method

Abstract

The invention provides a particle mobility mass spectrometer and a particle analysis method. The particle mobility mass spectrometer comprises an ion trap, a charge detector and a drift gas input system; the ion trap comprises an upper termination electrode, a lower termination electrode and a ring electrode, insulation structures are arranged between the upper and lower termination electrodes andthe ring electrode respectively, the ring electrode is provided with a sample inlet, and the upper and lower termination electrodes are provided with a drift gas inlet and a sample outlet respectively; the charge detector is arranged under the ion trap, and the sample outlet is arranged opposite to the charge detector; and the drift gas input system is positioned on the ion trap, and comprises agas introducing pipe, the tail end of the gas introducing pipe is aligned with the drift gas inlet, and the gas introducing pipe is provided with a gas valve. The particle mobility mass spectrometer can measure the weight, particle size and density of large molecular weight particles simultaneously, and the technical problem that an ion mobility mass spectrum cannot be used to analyze the particlesubstances of large molecular weight effectively in the prior art is solved.

Description

technical field [0001] The invention relates to the technical field of analysis of granular material structures, in particular to a particle mobility mass spectrometer and a particle analysis method. Background technique [0002] Particulate matter such as aerosols, cells and functional materials play important roles in nature. The functions of these particles, such as aerosol toxicity, cell growth, differentiation and apoptosis, and photoelectric properties of materials, are all determined by their structure, such as mass, particle size and density. To achieve the analysis of the structure of particulate matter, a series of different methods have been developed. However, these methods can only measure the specific structural parameters of particles, such as Coulter counter for the determination of particle volume, density gradient centrifugation for the determination of particle density, phase contrast microscopy and cantilever resonance for the determination of particle m...

AI Technical Summary

Problems solved by technology

[0005] The main purpose of the present invention is to provide a particle mobility mass spectrometer and a particle analysis method. The particle mobility mass spectrometer has two working modes of mass spectrometry and mobility spectrometry, and the two working modes can be easily switched. The combined determination of mass spectrometry can measure the mass, particle size and density of large molecular weight particles at the same time, so as to solve the technical problem that ion mobility mass spectrometry cannot effectively analyze the particulate matter with large molecular weight in the prior art

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