Eureka AIR delivers breakthrough ideas for toughest innovation challenges, trusted by R&D personnel around the world.

Ophthalmic postoperative flushing liquid and preparation method thereof

A technology of ophthalmic surgery and flushing solution, applied in the field of flushing solution, can solve the problems that need to be improved, easily produce precipitation and sterilization effect, and achieve the effect of avoiding drug precipitation and improving sterilization efficiency

Active Publication Date: 2019-08-23
葛强
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to solve the technical problems that the ophthalmic flushing liquid in the prior art is prone to precipitation and the bactericidal effect needs to be improved, and proposes a flushing liquid for ophthalmic surgery and its preparation method

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Ophthalmic postoperative flushing liquid and preparation method thereof
  • Ophthalmic postoperative flushing liquid and preparation method thereof
  • Ophthalmic postoperative flushing liquid and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A kind of flushing solution after eye surgery proposed by the present invention comprises the following raw materials in parts by weight: 10 parts of sodium carboxymethyl cellulose, 10 parts of sodium alginate, 30 parts of sodium chloride, 17 parts of povidone-iodine, compound ( 1) 51 parts, 1100 parts of medical purified water. Wherein, the structural formula of compound (I) is

[0024]

[0025] A kind of preparation method of flushing liquid after ophthalmic surgery proposed by the present invention comprises the following steps,

[0026] S1, put povidone-iodine and compound (I) in a sterile stirrer and stir fully, the stirring time is 3min, the reaction temperature is 20°C, and mixed liquid A is obtained;

[0027] S2, put the remaining raw materials into medical purified water according to the weight ratio, and put them together into a sterile reaction kettle, the stirring time is 15min, and the reaction temperature is 30°C to obtain the mixed liquid B;

[0028]...

Embodiment 2

[0032] A kind of flushing solution after eye surgery proposed by the present invention comprises the following raw materials in parts by weight: 15 parts of sodium carboxymethyl cellulose, 15 parts of sodium alginate, 35 parts of sodium chloride, 15 parts of povidone-iodine, compound ( 1) 45 parts, 1200 parts of medical purified water. Wherein, the structural formula of compound (I) is

[0033]

[0034] A kind of preparation method of flushing liquid after ophthalmic surgery proposed by the present invention comprises the following steps,

[0035] S1, put povidone-iodine and compound (I) in a sterile stirrer and fully stir, the stirring time is 4min, and the reaction temperature is 30°C to obtain a mixed liquid A;

[0036] S2, put the remaining raw materials into medical purified water according to the weight ratio, and put them together into a sterile reaction kettle, the stirring time is 20min, and the reaction temperature is 40°C to obtain the mixed liquid B;

[0037] ...

Embodiment 3

[0041] A kind of flushing solution after eye surgery proposed by the present invention comprises the following raw materials in parts by weight: 20 parts of sodium carboxymethyl cellulose, 20 parts of sodium alginate, 40 parts of sodium chloride, 20 parts of povidone-iodine, compound ( 1) 60 parts, 1300 parts of medical purified water. Wherein, the structural formula of compound (I) is

[0042]

[0043] A kind of preparation method of flushing liquid after ophthalmic surgery proposed by the present invention comprises the following steps,

[0044] S1, put povidone-iodine and compound (I) in a sterile stirrer and fully stir, the stirring time is 5min, and the reaction temperature is 40°C to obtain a mixed liquid A;

[0045] S2, put the remaining raw materials into medical purified water according to the weight ratio, and put them together into a sterile reaction kettle, the stirring time is 25min, and the reaction temperature is 50°C to obtain the mixed liquid B;

[0046] ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an ophthalmic postoperative flushing liquid and a preparation method thereof. The ophthalmic postoperative flushing liquid comprises, by weight, 10-20 parts of sodium carboxymethyl cellulose, 10-20 parts of sodium alginate, 30-40 parts of sodium chloride, 15-20 parts of povidone iodine, 45-60 parts of a compound (I) and 1100-1300 parts of medical purified water. The prepared flushing liquid is good in stability, free of precipitation and high in sterilization efficiency, has a good protection effect on the wound of a patient and is suitable for popularization, and the preparation method is reasonable.

Description

technical field [0001] The invention relates to a flushing liquid technology, in particular to a flushing liquid for ophthalmic surgery and a preparation method thereof. Background technique [0002] Ophthalmic surgery often requires the application of physiological irrigation fluids to protect and maintain the physiological integrity of intraocular tissues. Examples of ophthalmic surgical procedures that typically require irrigation are cataract surgery, corneal transplant surgery, vitreoretinal surgery, and trabeculectomy for glaucoma. The health administrative department divides ophthalmic surgery into four levels according to the difficulty of medical technology. After ophthalmic surgery, patients are prone to various intraocular and extraocular symptoms such as lens swelling, corneal inflammation, and even aqueous humor leakage, resulting in slow recovery and even surgical failure. Therefore, various irrigation solutions must be used after ophthalmic surgery to regulat...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K9/08A61K31/79A61K31/4178A61K47/36A61K47/38A61K47/02A61P27/02A61P31/04
CPCA61K9/0048A61K9/08A61K31/4178A61K31/79A61K47/02A61K47/36A61K47/38A61P27/02A61P31/04A61K2300/00
Inventor 李承坤
Owner 葛强
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com