Wearable glucose sensor chip based on working electrodes of gold aerogel and preparation method of wearable glucose sensor chip

Abstract

The invention relates to a wearable glucose sensor chip based on working electrodes of gold aerogel and a preparation method of the wearable glucose sensor chip. The gold aerogel is directly used as the working electrodes of wearable glucose sensors, no additional conductive substrate is required, the accuracy of detecting the glucose concentration is improved, the cost of making the conductive substrate is also saved, and the cost performance of a sensor is improved; and in addition, by adjusting parameters of the synthetic gold aerogel, the gold aerogel with different sizes is prepared to prepare the working electrodes of the glucose sensors with different sensitivities, and the signal-to-noise ratio of the sensor is greatly increased.

Description

technical field [0001] The invention belongs to the technical fields of nanomaterials, electrochemical detection and microelectromechanical structures (MEMS), and relates to a wearable glucose sensor chip based on gold airgel working electrodes and a preparation method. Background technique [0002] The detection of glucose content is of great significance for the early detection and treatment of diseases involving abnormal blood sugar content such as diabetes and hyperglycemia. Not only that, accurate, real-time and convenient blood sugar detection is an important basis for clinical medicine, human physiology and other research fields. [0003] Glucose sensor, as a biosensor that is sensitive to biological substances and converts its concentration into electrical signals, has a wide range of application backgrounds. The technology of glucose sensor in the prior art is divided into two methods: enzyme-based and non-enzymatic. The glucose sensor with enzyme uses glucose oxid...

AI Technical Summary

Problems solved by technology

The technology of glucose sensor in the prior art is divided into two methods: enzyme-based and non-enzymatic. The glucose sensor with enzyme uses glucose oxidase or glucose dehydrogenase to detect qualitatively and quantitatively glucose, but the enzyme activity will be affected Due to the influence of the external environment, the sensitivity and long-term stability of the sensor will be limited; most enzyme-free glucose sensors use metals or metal oxides to catalyze the oxidation of glucose, but this technology is mostly suitable for detecting glucose under alkaline conditions, not suitable for For wearable sensor field

[0004] In the prior art, there is no invention technology that uses gold aerogel directly as the working electrode, and the glucose sensor close to the technology of the present invention has a layer of metal or other materials (such as conductive polymer) on the substrate of the working electrode. object) conductive substrate, its disadvantage is that in addition to the conductive function, the conductive substrate also interferes with the detection of glucose due to its own catalytic properties, and cannot truly reflect the measured value of the real working electrode (modified object), resulting in errors

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