Degradation type bone repairing material

A technology of bone repair and solid material, applied in medical science, tissue regeneration, prosthesis, etc., can solve the problems of non-degradation of inert bone cement, non-fusion of bone tissue, collapse and rupture of vertebral body, etc., and achieve the effect of accelerating the setting time.

Inactive Publication Date: 2019-09-17
太仓新亚逊生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the biggest problem is that the inert bone cement does not degrade and does not fuse with the bone tissue. After a few years, it will be like a hard s

Method used

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Embodiment

[0014] Embodiment: A degradable bone repair material, the present invention includes a mixed solid material and a liquid phase, the mixed solid material includes bioactive glass, calcium phosphate and magnesium hydroxysilicate, and the liquid phase includes a blending solution, wherein the The particle size of the bioactive glass is less than 50 μm, the particle size of the calcium phosphate is less than or equal to 100 μm, and the particle size of the magnesium hydroxysilicate is less than or equal to 100 μm.

[0015] The composition of the mixed solid material includes: by weight percentage, 15%-30% of bioactive glass, 30%-45% of calcium phosphate, and 30%-40% of magnesium hydroxysilicate; the mixed solid material and the liquid The mixing ratio of the phases is 1g:0.3ml-1g:0.8ml.

[0016] The composition of the mixed solid material includes: by weight percentage, 27% of bioactive glass, 41.5% of calcium phosphate, and 31.5% of magnesium hydroxysilicate; the mixing ratio of ...

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Abstract

The invention discloses a degradation type bone repairing material, which comprises a mixed solid phase material and a liquid phase, wherein the mixed solid phase material comprises biological activity glass, calcium phosphate and magnesium silicate hydroxide, the liquid phase comprises blending solution, the particle size of the biological activity glass is smaller than 50[Mu]m, the particle size of the calcium phosphate is smaller than or equal to 100[Mu]m, and the particle size of the magnesium silicate hydroxide is smaller than or equal to 100[Mu]m. Through the above way, a biological activity glass-calcium phosphate-magnesium silicate hydroxide ternary system is adopted, so that the degradation type bone repairing material can be pushed for injection, exhibits ideal self-curing absorbability, can serve as a bone repairing substitute material, and can be used in percutaneous vertebroplasty, knee and hip joint replacement surgeries and other bone fracture surgeries.

Description

technical field [0001] The invention belongs to the technical field of medical biomaterials, in particular to a degradable bone repair material. Background technique [0002] With the development of biotechnology, the medical device industry, especially the orthopedic medical device technology and industry, is booming. At present, in orthopedic vertebroplasty and knee and hip replacement operations, bone cement is required to provide mechanical support or fixation of the replacement body. The number of vertebroplasty surgeries in China has increased from less than 20,000 per year in 2010 to 120,000 in 2015, with an expected annual growth rate of 15%. Vertebroplasty is for the injured patient's vertebral body to fracture and collapse for various reasons, causing pain and inability to move normally. The collapsed vertebral body must be propped up through surgery, so that the spine can slowly return to normal work and relieve the patient's pain. In knee and hip replacement su...

Claims

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Application Information

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IPC IPC(8): A61L27/12A61L27/10A61L27/02A61L27/50A61L27/58
CPCA61L27/025A61L27/10A61L27/12A61L27/50A61L27/58A61L2430/02
Inventor 陈华成
Owner 太仓新亚逊生物科技有限公司
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