Method and device for sleep deprivation, computer equipment and storage medium

A sleep deprivation and sleep technology, applied in the fields of computer equipment and storage media, devices, and sleep deprivation methods, can solve the problems of sleep deprivation, angle defects, and experimental animals stuck between food cages and rotating cages, and achieves improved accuracy. Effect

Active Publication Date: 2019-10-18
SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
View PDF5 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The forced exercise method is to force the experimental animals to move continuously through a power device (such as a rotating cage), so as to achieve the purpose of sleep deprivation, but long-term non-stop exercise will cause exercise stress and physical fatigue, which will become factors that interfere with sleep deprivation. Due to the angle defect between the food cage and the rotating cage, sometimes the head of the experimental animal gets stuck between the food cage and the rotating cage, causing injury or death of the experimental animal; the physical stimulation method is that the experimental animal is subjected to physical stimulation to keep awake, and needs to be studied. Personnel perform the operation of applying physical stimulation, but this method can easily lead to sleep deprivation of researchers, resulting in large errors, so it is more suitable for short-term sleep deprivation experiments, and physical stimulation may cause damage to experimental animals, making it impossible to study the natural state The sleep state of the

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method and device for sleep deprivation, computer equipment and storage medium
  • Method and device for sleep deprivation, computer equipment and storage medium
  • Method and device for sleep deprivation, computer equipment and storage medium

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] figure 1 It is a flow chart of a sleep deprivation method provided by Embodiment 1 of the present invention. This embodiment is applicable to the situation of sleep deprivation for animals. The method is executed by a sleep deprivation device, which can be implemented by software and / or hardware , generally can be integrated in computer equipment, the method specifically includes the following steps:

[0024] S110, pre-introducing a set gene into a set cell in the target animal, wherein the set cell is a neuron cell involved in the regulation mechanism of awake sleep behavior, and the set gene includes an excitatory protein gene and an inhibitory protein gene .

[0025] In this embodiment, the method of light regulation is used to excite the cells used to suppress sleep in the target animal, or to reduce the excitability of the cells used to enter sleep in the target animal, so that the target animal enters from a sleep state. Awakening state, to achieve the effect of...

Embodiment 2

[0047] figure 2 It is a flowchart of a sleep deprivation method provided by Embodiment 2 of the present invention. This embodiment is embodied on the basis of the above embodiments, and the physiological signals are embodied as cortical EEG signals, hippocampal field electrical signals and EMG signal. Such as figure 2 As shown, the method specifically includes the following steps:

[0048] S210, pre-introducing a set gene into a set cell in the target animal, wherein the set cell is a neuron cell involved in the regulation mechanism of awake sleep behavior, and the set gene includes an excitatory protein gene and an inhibitory protein gene .

[0049] S220. Collect physiological signals of the target animal, where the physiological signals include cortical EEG signals, hippocampal field electrical signals, and myoelectric signals.

[0050] In this embodiment, by collecting electrical signals (including cortical EEG signals, hippocampal field electrical signals and myoelec...

Embodiment 3

[0065] image 3 It is a schematic diagram of the sleep deprivation device provided by Embodiment 3 of the present invention. The third embodiment is a corresponding device for implementing the sleep deprivation method provided by the above embodiments of the present invention.

[0066] The gene introduction module 310 is used to pre-introduce a set gene into a set cell in a target animal, wherein the set cell is a neuron cell involved in the regulation mechanism of awake sleep behavior, and the set gene includes an excitatory protein gene and repressor protein genes;

[0067] A physiological signal receiving module 320, configured to collect the physiological signal of the target animal;

[0068] A control signal output module 330, configured to use a set light control signal to perform light control on the set cell when it is determined that the physiological signal is a sleep signal, wherein the set light control signal is a light beam with a set wavelength , for activati...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The embodiment of the invention discloses a method and device for sleep deprivation, computer equipment and a storage medium. The method comprises the following steps of introducing set genes to set cells in a target animal body in advance, wherein the set cells are neuron cells participating in a waking-sleeping behavior adjusting and controlling mechanism, and the set genes comprise excited typeprotein genes and inhibitable type protein genes; acquiring a physiological signal of a target animal; and when the situation that the physiological signal is a sleep signal is determined, using a set light adjusting and controlling signal to perform light adjusting and controlling on the set cells, wherein the set light adjusting and controlling signal is a light beam having a set wave length, and is used for activating the set genes. Through the adoption of the method disclosed by the embodiment of the invention, a conventional sleep deprivation method is optimized, the reliability of a sleep deprivation test is improved, and the accuracy of test data is guaranteed.

Description

technical field [0001] Embodiments of the present invention relate to the technical field of sleep deprivation, and in particular, to a sleep deprivation method, device, computer equipment, and storage medium. Background technique [0002] Sleep is a spontaneous and reversible resting state of the brain that occurs periodically in higher vertebrates. It is a decrease in the body's response to external sensory stimuli and a short interruption of consciousness. Studies have shown that sleep is closely related to learning and memory, regulation of the biological clock, metabolism of organisms, immunity, and secretion of hormones. Sleep disorders can affect abnormal changes in brain thinking, memory, emotion, immunity, etc., and are closely related to the occurrence of mental diseases and may also lead to neurometabolic, neuroimmune, and neuroendocrine-related diseases. [0003] At present, in order to study the influence of sleep on organisms, researchers usually deprive exper...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61M21/00
CPCA61M21/00A61M2021/0005
Inventor 刘雪梅刘远明陈晨曾鹏宇彭圳杰刘雪王立平
Owner SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap