Dietary supplement ginseng and sea cucumber capsule for weak patients after illness and preparation method thereof
A technology for dietary supplementation and post-illness weakness, applied in capsule delivery, medical preparations containing active ingredients, applications, etc., can solve the problem of patients' physical and quality of life recovery in the later stage, lack of bone marrow hematopoietic function decline, and poor patient compliance problems such as reducing medical burden, reducing the occurrence of anemia and myelosuppression, and simplifying the preparation
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Embodiment 1
[0029] The chemotherapeutic drug epirubicin (0.4mg / body) was used for two consecutive days to make a bone marrow suppression model, 5 animals; the normal group: 5 animals; / ml, twice / day) (ginseng and sea cucumber ratio 1:1), 5 pieces; Epirubicin + Bazhen Decoction (0.2ml / piece, containing crude drug 0.2g / ml, twice / day), 5 pieces They were observed for one week and executed two weeks later. The sternum was removed for HE staining and immunohistochemical staining for hematopoietic stem cell marker CD34.
[0030] The results are as follows: The statistical analysis of the number of platelet-producing cells megakaryocytes is as follows: figure 1 shown.
[0031] The results showed that Shuangshen Capsules could resist the thrombocytopenia caused by epirubicin, and the effect was basically the same as that of Bazhen Decoction.
Embodiment 2
[0033] The chemotherapeutic drug epirubicin (0.4mg / body) was used for two consecutive days to make a bone marrow suppression model, 5 animals; the normal group: 5 animals; / ml, twice / day) (ginseng and sea cucumber ratio 1:2), 5 pieces; Epirubicin + Bazhen Decoction (0.2ml / piece, containing crude drug 0.2g / ml, twice / day), 5 pieces They were observed for one week and executed two weeks later. The sternum was removed for HE staining and immunohistochemical staining for hematopoietic stem cell marker CD34.
[0034] result figure 2 Shown, the statistical analysis of the number of CD34 positive hematopoietic stem cells.
[0035] The results showed that: epirubicin significantly reduced the number of bone marrow hematopoietic stem cells, and the bone marrow suppression effect was obvious. Shuangshen Capsules could significantly counteract this effect of epirubicin, and the effect was stronger than that of Bazhen Decoction, especially in the first week. In the second week, it can m...
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