Traditional Chinese medicine composition with protective function on alcoholic liver injury and preparation method thereof
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A technology for alcohol-induced liver injury and protective function, which can be applied in drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., and can solve problems such as acute alcoholism
Inactive Publication Date: 2019-11-22
JILIN ACAD OF TRADITIONAL CHINESE MEDICINE
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Problems solved by technology
[0003] Drinking a lot of alcohol at one time often leads to acute alcoholism
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Embodiment 1
[0016] 2 parts of kudzu root, 2 parts of Hovenia dulcis, 2 parts of white peony, 2 parts of licorice;
[0017] Take the above-mentioned proportion of raw materials by weight and feed, soak for 30 minutes, extract with 8 times the amount of water three times, each time for 1 hour, filter, concentrate under reduced pressure, 70°C, -0.06Mpa, and measure 1.05 when the relative density reaches 60°C; Spray drying, the inlet air temperature is 150°C, and the outlet air temperature is 80°C to obtain dry cream powder.
Embodiment 2
[0019] 6 parts of kudzu root, 5 parts of Hovenia dulcis, 7 parts of white peony, 6 parts of licorice;
[0020] Feed the above-mentioned proportion of raw materials by weight, soak for 30 minutes, extract with 8 times the amount of water three times, each time for 1 hour, filter, concentrate under reduced pressure, 72.5°C, -0.07Mpa, and measure 1.08 when the relative density reaches 60°C; Spray drying, the inlet air temperature is 155°C, and the outlet air temperature is 82.5°C to obtain dry cream powder.
Embodiment 3
[0022] 10 parts of kudzu root, 9 parts of Hovenia dulcis, 10 parts of white peony, 9 parts of licorice;
[0023] Feed the above-mentioned proportion of raw materials by weight, soak for 30 minutes, extract with 8 times the amount of water three times, each time for 1 hour, filter, concentrate under reduced pressure, 75°C, -0.08Mpa, and measure 1.10 when the relative density reaches 60°C; Spray drying, the inlet air temperature is 160°C, and the outlet air temperature is 85°C to obtain dry cream powder.
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Abstract
The invention provides a traditional Chinese medicine composition with a protective function on alcoholic liver injury and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from, by weight, 2-10 parts of radix puerariae, 2-10 parts of hovenia dulcis thunb, 2-10 parts of radix paeoniae alba and2-10 parts of licorice root. The traditional Chinese medicine composition has the effects of relieving alcoholism, helping produce saliva and slaking thirst, smoothing liver and relieving pain. The traditional Chinese medicine theory and the modern scientific theory serve as guidance, L9(34) orthogonal compatibility testing is used, the compatibility proportion of the raw material components is determined with extremely-low-density lipoprotein in serum of miceand malonaldehyde and glutathione in the liver as indexes, and the traditional Chinese medicine composition with the protective function on alcoholic liver injury is prepared. Pharmacodynamic research shows that the composition can be used for improving related indexes of the acute and subacute alcoholic liver injury mice. The composition is suitable for boozy people, and is clear in effective component and controllable in quality.
Description
technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition, which has a protective function against alcoholic liver damage and a preparation method. Background technique [0002] Alcoholic liver injury mainly refers to alcoholic fatty liver, alcoholic hepatitis, alcoholic liver fibrosis and alcoholic liver cirrhosis. Extensive liver cell necrosis or even liver failure can be induced in severe alcoholism. Alcoholic liver disease is the most common liver disease in western countries, and its incidence is increasing in our country. [0003] Drinking more alcohol at one time often leads to acute alcoholism. After acute alcoholism, it is often accompanied by various physical discomforts such as headache, nausea, and general fatigue, which may be life-threatening in severe cases. Chronic alcoholism (alcohol dependence) is also a disease, which is a systemic syndrome caused by th...
Claims
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