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Chicory polysaccharide as well as extraction process and application thereof

An extraction process, the technology of chicory polysaccharides, which is applied in the direction of medical preparations containing active ingredients, organic active ingredients, bone diseases, etc., can solve problems such as imperfections, and achieve the effect of simple extraction and high extraction rate

Inactive Publication Date: 2019-12-03
WUHAN POLYTECHNIC UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current research on chicory’s ability to lower uric acid is relatively incomplete. In order to better play the role of chicory, it is necessary to conduct in-depth research on its extraction process and food functions.

Method used

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  • Chicory polysaccharide as well as extraction process and application thereof
  • Chicory polysaccharide as well as extraction process and application thereof
  • Chicory polysaccharide as well as extraction process and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0034] This embodiment provides an extraction process of chicory polysaccharide. Proceed as follows:

[0035] Step 1: Select chicory roots, use 55% ethanol solution as extraction solvent, temperature 62°C, and material-liquid ratio 1:20.

[0036] Step 2: The alcohol extract in step 1 is extracted with ultrasonic assistance, the ultrasonic power is 160W, the extraction times are 2 times, and each time is 0.5h minutes.

[0037] Step 3: Perform ultrafiltration of the extract in step 2. The ultrafiltration membrane used for ultrafiltration is polycarbonate to obtain chicory polysaccharide; the ultrafiltration temperature is 46-55°C, the time is 8-15 minutes, and the flow rate is 40-60ml / min, the pressure is 130-160KPa.

Embodiment 2

[0039] This embodiment provides an extraction process of chicory polysaccharide. Proceed as follows:

[0040] Step 1: Select chicory root, use 60% ethanol solution as extraction solvent, temperature 68°C, and material-liquid ratio 1:10.

[0041] Step 2: The alcohol extract in step 1 is extracted with ultrasonic assistance, the ultrasonic power is 175W, the extraction times are 3 times, and each time is 1 h minutes.

[0042] Step 3: Perform ultrafiltration of the extract in step 2, and the ultrafiltration membrane used for ultrafiltration is polyvinylidene fluoride to obtain chicory polysaccharide; the ultrafiltration temperature is 49° C., time is 12 minutes, flow rate is 50 ml / min, and pressure is 130 KPa.

Embodiment 3

[0044] This embodiment provides an extraction process of chicory polysaccharide. The process steps are as follows:

[0045] Step 1: Choose chicory root, use 80% ethanol solution as extraction solvent, temperature 70°C, and material-liquid ratio 1:25.

[0046] Step 2: The alcohol extract in step 1 is extracted with ultrasonic assistance, the ultrasonic power is 200W, the extraction times are 5 times, and each time is 1.5h minutes.

[0047] Step 3: Perform ultrafiltration of the extract in step 2, and the ultrafiltration membrane used for ultrafiltration is cellulose acetate to obtain chicory polysaccharide; the ultrafiltration temperature is 55° C., time is 15 minutes, flow rate is 60 ml / min, and pressure is 160 KPa.

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Abstract

The invention provides a chicory polysaccharide as well as an extraction process and application thereof. The extraction process of the chicory polysaccharide comprises the following steps: selectingchicory roots, taking a 40-80% ethanol solution as an extraction solvent, and performing ultrasonic assisted extraction at a temperature of 50-70 DEG C with a material liquid ratio of (1-5):(20-40), wherein the ultrasonic power is 150-250W, the extraction times are 2-5, each time of extraction lasts for 0.5-2 hours, the ultrafiltration temperature is 46-55 DEG C, the time is 8-15 minutes, the flowis 40-60ml / minute, and the pressure is 130-200KPa. The extraction method of the chicory polysaccharide is simple in extraction and high in extraction power, and the extraction rate of the chicory polysaccharide can be up to 23%. The chicory polysaccharide provided by the invention can be adopted to prepare specific dietary foods or medicinal foods for assisting uric acid reduction and preventinggout, is capable of effectively preventing or treating gout caused by monosodium urate crystals and provides novel products for preventing and treating gout.

Description

Technical field [0001] The invention belongs to the technical field of extraction of natural active substances, and specifically relates to a chicory polysaccharide and its extraction process and application. Background technique [0002] Gout (gout) is a group of heterogeneous diseases caused by long-term purine metabolism disorder and increased blood uric acid. The clinical features are hyperuricemia (HUA), recurrent gouty acute arthritis, goutstone deposition, characteristic chronic arthritis and joint deformities, often involving the kidneys and causing chronic interstitial nephritis and renal uric acid stone formation. The biochemical marker of gout is hyperuricemia, which refers to the supersaturation of urate in the extracellular fluid. Urate (monosodium urate crystal, MSU) deposits in the form of crystals in the joints and surrounding tissues, causing a series of acute inflammatory reactions, that is, gout. It is generally believed that 416μmol / L of blood uric acid blue...

Claims

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Application Information

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IPC IPC(8): C08B37/00A61K31/715A61P19/06
CPCA61K31/715A61P19/06C08B37/0003
Inventor 刘志伟李明王海琦白金雷帆
Owner WUHAN POLYTECHNIC UNIVERSITY
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