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Traditional Chinese medicine composition with hypoglycemic effect, and preparation method and application thereof

A composition and technology for lowering blood sugar, which can be used in drug combinations, medical preparations containing active ingredients, applications, etc., and can solve problems such as lack of hypoglycemic effect

Active Publication Date: 2019-12-27
THE SECOND XIANGYA HOSPITAL OF CENT SOUTH UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is still a lack of traditional Chinese medicine prescriptions with ideal hypoglycemic effect

Method used

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  • Traditional Chinese medicine composition with hypoglycemic effect, and preparation method and application thereof
  • Traditional Chinese medicine composition with hypoglycemic effect, and preparation method and application thereof
  • Traditional Chinese medicine composition with hypoglycemic effect, and preparation method and application thereof

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Effect test

Embodiment 1

[0039] The preparation of embodiment 1 Chinese medicine composition of the present invention and granule

[0040] Prescription: 300 parts of Astragalus, 350 parts of Polygonatum, 250 parts of Pueraria Radix, 200 parts of Salvia Miltiorrhiza, 150 parts of Radix Ophiopogon japonicus, 150 parts of Jiaogulan.

[0041]Preparation method: Weigh the above six traditional Chinese medicines in proportion, add water to decoct twice, add 8 times of water for the first time, decoct for 1.5 hours; add 6 times of water for the second time, decoct for 1 hour, filter, combine the filtrate, reduce Concentrate under pressure to a thick paste with a relative density of about 1.25-1.30 (measured at 60°C), vacuum-dry (drying temperature is 60-70°C, vacuum degree is -0.07--0.08Mpa) to obtain a dry paste, and crush it to obtain a dry paste about 500 g of powder to obtain the composition of the present invention.

[0042] Add 500 g of dextrin, 2 g of stevia, and 90% ethanol to granulate (16-mesh sie...

Embodiment 2

[0043] The preparation of embodiment 2 Chinese medicine composition of the present invention and granule

[0044] Prescription: a Chinese medicine composition granule for reducing hyperglycemia, comprising the following Chinese medicines in parts by weight: 350 parts of Radix Astragali, 250 parts of Polygonatum, 300 parts of Pueraria Radix, 300 parts of Salvia Miltiorrhiza, 200 parts of Ophiopogon japonicus, and 150 parts of Jiaogulan.

[0045] Preparation method: Weigh the above six traditional Chinese medicines in proportion, add water to decoct twice, add 8 times of water for the first time, decoct for 1.5 hours; add 6 times of water for the second time, decoct for 1 hour, filter, combine the filtrate, reduce Concentrate under pressure to a thick paste with a relative density of about 1.25-1.30 (measured at 60°C), vacuum-dry (drying temperature is 60-70°C, vacuum degree is -0.07--0.08Mpa) to obtain a dry paste, and crush it to obtain a dry paste about 500 g of powder to obt...

Embodiment 3

[0047] The preparation of embodiment 3 Chinese medicine composition of the present invention and granule

[0048] Prescription: a Chinese medicine composition granule for reducing hyperglycemia, including being made of the following Chinese medicines in parts by weight: 360 parts of Radix Astragali, 288 parts of Rhizoma Polygonatum, 288 parts of Radix Puerariae, 288 parts of Salvia Miltiorrhiza, 180 parts of Ophiopogon japonicus, 180 parts of Jiaogulan.

[0049] Preparation method: Weigh the above six traditional Chinese medicines in proportion, add water to decoct twice, add 8 times of water for the first time, decoct for 1.5 hours; add 6 times of water for the second time, decoct for 1 hour, filter, combine the filtrate, reduce Concentrate under pressure to a thick paste with a relative density of about 1.25-1.30 (measured at 60°C), vacuum-dry (drying temperature is 60-70°C, vacuum degree is -0.07--0.08Mpa) to obtain a dry paste, and crush it to obtain a dry paste about 500 ...

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Abstract

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition with a hypoglycemic effect, and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 300-400 parts of radix astragali, 200-350 parts of rhizoma polygonati, 200-350 parts of radix puerariae lobatae, 200-350 parts of radix et rhizoma salvia miltiorrhiza, 120-250 parts of radix ophiopogonis and 120-250 parts of fiveleaf gynostemma herb. According to the theory of traditional Chinese medicine, the radix astragali, the rhizoma polygonati, the radix puerariae lobatae, the radix et rhizoma salvia miltiorrhiza, the radix ophiopogonis and the fiveleaf gynostemma herb are combined reasonably, and the obtained composition has the significant hypoglycemic effect, has no toxic and side effect and has good market promotion value and medical application value.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition with hypoglycemic effect and its preparation method and application. Background technique [0002] Diabetes mellitus is a metabolic disease characterized by hyperglycemia due to relative insulin deficiency or insulin resistance. Fat and protein metabolism disorders in diabetic patients, clinical manifestations such as polyuria, polydipsia, polydipsia, polyphagia, and weight loss may occur. Long-term high blood sugar is prone to acute complications such as ketoacidosis or chronic complications such as blood vessels and nerves. In 2017, the prevalence of diabetes in my country was as high as 11.6%, and the number of patients was 114.4 million, ranking first in the world. It is expected to reach about 150 million by 2045. [0003] At present, the treatment of this disease mainly focuses on controlling blood sugar and ...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P3/10A23L33/105
CPCA61K36/481A61K36/8969A61K36/488A61K36/537A61K36/8968A61K36/424A61P3/10A23L33/105A61K2236/331A61K2236/39A23V2002/00A61K2300/00A23V2200/328A23V2250/21
Inventor 向大雄
Owner THE SECOND XIANGYA HOSPITAL OF CENT SOUTH UNIV
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