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Cogon grass rhizome, rhubarb charcoal and panax notoginseng composition and use thereof in regulating intestinal microorganisms

A technology for regulating intestinal tract and composition, applied in the field of impermanent rhubarb rhubarb charcoal notoginseng composition, improving and regulating intestinal microorganisms, and can solve problems such as impact

Pending Publication Date: 2019-12-27
ZHUHAI QLWEL BIO TECH LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although it is not clear whether the changes in the gut microbiota cause the occurrence of metabolic diseases, or the occurrence of metabolic diseases leads to the changes in the gut microbiota, but one thing is certain: by changing the gut microbiota The composition of the group has an impact on the health of the human body, and may also help the treatment of certain diseases

Method used

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  • Cogon grass rhizome, rhubarb charcoal and panax notoginseng composition and use thereof in regulating intestinal microorganisms
  • Cogon grass rhizome, rhubarb charcoal and panax notoginseng composition and use thereof in regulating intestinal microorganisms
  • Cogon grass rhizome, rhubarb charcoal and panax notoginseng composition and use thereof in regulating intestinal microorganisms

Examples

Experimental program
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Effect test

Embodiment 1

[0039] The preparation of embodiment 1 rhubarb rhubarb charcoal Panax notoginseng composition medicated powder

[0040] Prescription: Rhizoma Imperatae 40g, Rhubarb Charcoal 10g, Panax notoginseng 12g. The required Chinese herbal pieces, Rhizoma Imperatae, Rhubarb Charcoal, and Panax notoginseng were purchased from Guangdong Provincial Hospital of Traditional Chinese Medicine. The corresponding prescription doses of medicines were taken and dried in a low-temperature drying oven. The temperature range: 30-40°C, and the humidity range: 10-20°C. %RH, so that the surface moisture of the medicine is ≤0.5%, and then the dried medicine is input into the pulverizer in time while it is hot for pulverization, pulverized to 900 mesh, and the medicine powder is sterilized and then vacuum-packed for use.

Embodiment 2

[0041] Example 2 Ethanol extraction method to prepare the extract of rhubarb rhubarb and charcoal notoginseng composition

[0042] Prescription: 20g of rhubarb root, 3g of rhubarb charcoal, 6g of notoginseng. Take the drug corresponding to the prescription dose, crush the drug into 20-mesh drug powder, extract the coarse drug powder three times with 80% ethanol solution, filter the extract and concentrate under reduced pressure to obtain a drug concentrate, and elute the concentrate through an adsorption column. The packing of the adsorption column is HPD100, which is firstly washed with purified water to remove impurities, and then eluted with 60%, 70%, and 80% ethanol to obtain an eluate, which is concentrated under reduced pressure, decolorized, refined, and concentrated under reduced pressure to immersion Paste, after freeze-drying to obtain the extract of traditional Chinese medicine composition.

Embodiment 3

[0043] Example 3 Water decoction method to prepare the extract of rhubarb rhubarb and charcoal notoginseng composition

[0044] Prescription: Rhizoma Imperatae 30g, Rhubarb Charcoal 6g, Panax notoginseng 9g. Take the medicine of the corresponding prescription dose, put it in a suitable decocter, add about 600ml of water to immerse the medicinal material for 1 hour, boil it and heat it for 0.5 hour, separate the decocted liquid, and continue to decoct the medicine dregs for the second time, the decocted liquid is the same as the first decocted liquid Mix and measure the volume with a measuring cylinder. If the volume exceeds 600ml, further boil the decoction and concentrate it to about 600ml. After reaching the corresponding volume, boil the decoction and vacuum pack it into 7-8 small bags, and store it at 4°C for later use. use.

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Abstract

The invention provides a cogon grass rhizome, rhubarb charcoal and panax notoginseng composition, a use of the cogon grass rhizome, rhubarb charcoal and panax notoginseng composition in regulating intestinal microorganisms, and an application thereof in preparation of a drug, wherein the drug is a drug for treating diseases related to intestinal flora disorders.

Description

technical field [0001] The invention belongs to the field of medicine and health care, and in particular relates to the application of the rhubarb rhubarb and charcoal notoginseng composition in improving and regulating intestinal microorganisms. Background technique [0002] There are a large number of symbiotic microorganisms in the human body, especially 1000-1150 kinds of about 100 trillion bacteria in the human intestinal tract, which are the most important "endogenous environmental factors" of the human body, and the number of them is about 10 times that of the human body's own cells. Under normal circumstances, intestinal microorganisms are in a dynamic and balanced ecological environment. Normal flora not only play an irreplaceable role in digestion, immunity and anti-virus, but also changes in intestinal microorganisms are closely related to body health or diseases, especially some chronic diseases. The occurrence of disease has a very close relationship. In the co...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P1/12A61P1/10A61P1/00A61P1/16A61P1/04A61P1/18A61P3/04A61P3/10A61P13/04A61P25/16A61P25/22A61P25/24A61P35/00
CPCA61K36/258A61K36/708A61K36/899A61P1/00A61P1/04A61P1/10A61P1/12A61P1/16A61P1/18A61P3/04A61P3/10A61P13/04A61P25/16A61P25/22A61P25/24A61P35/00A61K2300/00Y02A50/30
Inventor 魏来梁桥星葛小菲
Owner ZHUHAI QLWEL BIO TECH LTD