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Specially-compounded liquid for VLBWI (Very low birth weight infant) nutrition management and preparation method and application of specially-compounded liquid

A nutrition and solution preparation technology, applied in the field of nutrition, can solve the problems of not conforming to the fetal metabolic law and unsatisfactory effect, and achieve the effect of increasing the rate of weight growth, shortening the length of hospital stay, and optimizing biochemical indicators

Active Publication Date: 2020-01-07
SOOCHOW UNIV AFFILIATED CHILDRENS HOSPITAL
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  • Abstract
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AI Technical Summary

Problems solved by technology

[0005]The traditional parenteral nutrition supply program provides glucose supply within 24 hours, and amino acid and fat milk supply from 24-48 hours. This solution does not conform to the metabolic laws of the fetus , so the effect is not ideal

Method used

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  • Specially-compounded liquid for VLBWI (Very low birth weight infant) nutrition management and preparation method and application of specially-compounded liquid
  • Specially-compounded liquid for VLBWI (Very low birth weight infant) nutrition management and preparation method and application of specially-compounded liquid
  • Specially-compounded liquid for VLBWI (Very low birth weight infant) nutrition management and preparation method and application of specially-compounded liquid

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Embodiment

[0061] VLBWI nutrition management special solution 100ml, including: 6.7% pediatric compound amino acid (19AA-1) 40ml, 20% medium and long-chain fat emulsion 6ml, 10% sodium chloride injection 1ml, 10% potassium chloride injection 1ml, 10ml of 50% glucose injection, 40ml of 10% glucose injection, 1ml of water-soluble vitamin injection for injection, 1ml of fat-soluble vitamin injection (without adding potassium within three days after birth); Add 10% potassium chloride, 50% glucose injection, 6.7% pediatric compound amino acid (19AA-1), and water-soluble vitamins for injection to 10% glucose injection successively; ② Inject fat-soluble vitamins into 20% medium and long-chain fat emulsion ; ③ Inject the nutrient solution prepared in step ② into the nutrient solution prepared in step ①, and mix thoroughly to obtain a special solution for VLBWI nutrition management, which is used in the following research groups.

[0062] The parenteral nutrition program for the control group was...

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Abstract

The invention discloses specially-compounded liquid for VLBWI (Very low birth weight infant) nutrition management and a preparation method and application of the specially-compounded liquid. The preparation method comprises the step of mixing fat emulsion with amino acids, glucose, ionogram and vitamins under the aseptic condition so as to obtain the specially-compounded liquid for VLBWI (Very lowbirth weight infant) nutrition management, wherein the fat emulsion is a long-chain fat emulsion. A new scheme is provided for nutrition management of clinical premature very low birth weight infants. The specially-compounded liquid disclosed by the invention can reduce the occurrence rate of PNAC, NEC, BPD, hypoglycemia, ROP, late-onset type septicaemia and BIPI, is good in safety, besides, canreduce the occurrence rate of EUGR, can shorten hospital stays and can optimize the life quality of child patients.

Description

technical field [0001] The invention belongs to the technical field of nutrition, and in particular relates to the nutrition management of newborns, in particular to a special formula for VLBWI nutrition management and its preparation method and application. Background technique [0002] Very low birth weight infants (VLBWI) refer to newborns whose birth weight is less than 1500g. Because of the extremely immature development of various organ functions, various complications are prone to occur, unable to adapt to the external environment, and the mortality rate is relatively high. High (CAI W. Parenteral nutrition of newborn [J]. Clin Pediatr, 2004, 22 (4): 267-268). In recent years, with the development of reproductive technology and neonatal intensive care, the incidence of premature birth and VLBWI has been on the rise. Epidemiological studies by Law K S et al. pointed out that the incidence of VLBWI in British and American countries was 0.20% in 1985 and 0.57% in 1988. ...

Claims

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Application Information

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IPC IPC(8): A23L33/00
CPCA23L33/00A23V2002/00A23V2200/30A23V2200/324A23V2200/32A23V2200/314A23V2200/328A23V2250/06A23V2250/70A23V2250/61
Inventor 朱雪萍汪健朱晓黎陈小倩崔宁讯葛丽丽李萍
Owner SOOCHOW UNIV AFFILIATED CHILDRENS HOSPITAL
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