Method for preparing high-hydrophobicity film by electrostatic spinning

Abstract

The invention discloses a method for preparing a high-hydrophobicity film by electrostatic spinning. According to the method, a detachable mesh template with the pore diameter being 20-200 micrometersis fixed to the surface of a receiving machine of an electrostatic spinning machine; a hydrophobic polymer solution is jet to the micrometer-sized mesh template through the electrostatic spinning machine, and deposits to obtain hydrophobic fibers with nano-scale diameter; further, the high-hydrophobicity film is obtained after the mesh template is stripped. The high-hydrophobicity film prepared by the method has a micron-nano composite structure and has excellent bacterial adherence resistance performance; the preparation of biomedical dressing by the film is simple and convenient and raw materials for the preparation are green and cheap; the biomedical dressing prepared has better dressing hydrophobicity and higher bacterial adherence resistance performance.

Description

technical field [0001] The invention belongs to the field of biomedical dressings, and in particular relates to a method for preparing a strong hydrophobic membrane by electrospinning and an application thereof. Background technique [0002] The skin is the largest organ in the human body and plays an important role in homeostasis and protection from microbial invasion. Injuries to the skin can pose serious health risks to the human body. To avoid further complications, the wound needs to be covered immediately after a skin injury has occurred to protect the tissue from harmful substances and prevent fluid loss. [0003] An ideal wound dressing has the characteristics of keeping the wound environment moist, absorbing excess exudate, preventing exogenous infection, breathable, and allowing external gas exchange. However, most of the traditional dressings need to be replaced frequently, which is easy to cause secondary injury, and cannot effectively prevent exogenous infectio...

AI Technical Summary

Problems solved by technology

However, the hydrophobicity of the nano-hydrophobic layer in this patent only depends on the inherent hydrophobicity of the material itself, and the hydrophobicity is average, so its antibacterial performance is not ideal; at the same time, the patent improves the dressing by loading antibiotics on the hydrophilic layer. overall antimicrobial performance

However, inappropriate use of antibiotics can lead to new resistance mechanisms in bacteria, leading to their wider spread

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