Vitamin K2 (MK-7) soft capsule for promoting blood calcium to enter bones and preparation method thereof

A technology of blood calcium into bone and vitamins, applied in capsule delivery, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. and other problems, to achieve the effect of good taking effect, high stability and convenient taking.

Inactive Publication Date: 2020-03-24
SHAANXI HEMING HEALTH TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] Insufficient of traditional Chinese medicine treatment of osteoporosis: the quality standards of traditional Chinese medicine preparations are not uniform, lack of unified dialectical classification, diagnosis, treatment and curative effect judgment standards, lack of long-term observation and follow-up reports

Method used

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  • Vitamin K2 (MK-7) soft capsule for promoting blood calcium to enter bones and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] A vitamin K2 (MK-7) soft capsule that promotes blood calcium into the bone, including cyst fluid and capsule skin;

[0057] The cyst fluid is composed of the following raw materials in parts by weight:

[0058] Vitamin K2 30 parts, vegetable oil 440 parts, antioxidant 0.1 part;

[0059] Described rubber is made up of following raw materials in parts by weight:

[0060] 150 parts of gelatin and hydroxypropyl methylcellulose, 110 parts of purified water, 45 parts of plasticizer, 1 part of opacifier.

[0061] Above-mentioned vegetable oil is soybean oil and MCT oil, and the mass ratio of soybean oil and MCT oil is 2.5: 2.

[0062] The above antioxidant is L-ascorbyl palmitate.

[0063] The above-mentioned plasticizers are glycerin and sorbitol, and the mass ratio of glycerin and sorbitol is 3:4.

[0064] The above-mentioned opacifying agent is titanium dioxide.

[0065] The preparation method of a vitamin K2 (MK-7) soft capsule that promotes blood calcium to enter the b...

Embodiment 2

[0081] A vitamin K2 (MK-7) soft capsule that promotes blood calcium into the bone, including cyst fluid and capsule skin;

[0082] The cyst fluid is composed of the following raw materials in parts by weight:

[0083] Vitamin K2 60 parts, vegetable oil 530 parts, antioxidant 0.2 parts;

[0084] Described rubber is made up of following raw materials in parts by weight:

[0085] 220 parts of gelatin and hydroxypropyl methylcellulose, 180 parts of purified water, 80 parts of plasticizer, 6 parts of opacifier.

[0086] Above-mentioned vegetable oil is soybean oil and MCT oil, and the mass ratio of soybean oil and MCT oil is 2.5: 2.

[0087] The above antioxidant is L-ascorbyl palmitate.

[0088] The above-mentioned plasticizers are glycerin and sorbitol, and the mass ratio of glycerin and sorbitol is 3:4.

[0089] The above-mentioned opacifying agent is titanium dioxide.

[0090] The preparation method of a vitamin K2 (MK-7) soft capsule that promotes blood calcium to enter t...

Embodiment 3

[0106] A vitamin K2 (MK-7) soft capsule that promotes blood calcium into the bone, including cyst fluid and capsule skin;

[0107] The cyst fluid is composed of the following raw materials in parts by weight:

[0108] Vitamin K2 45 parts, vegetable oil 500 parts, antioxidant 0.15 parts;

[0109] Described rubber is made up of following raw materials in parts by weight:

[0110] 200 parts of gelatin and hydroxypropyl methylcellulose, 150 parts of purified water, 60 parts of plasticizer, 4 parts of opacifier.

[0111] The above-mentioned vegetable oils are soybean oil and MCT oil, and the mass ratio of soybean oil to MCT oil is 2.2:1.5.

[0112] The above antioxidant is L-ascorbyl palmitate.

[0113] The above-mentioned plasticizers are glycerin and sorbitol, and the mass ratio of glycerin and sorbitol is 2.5:3.

[0114] The above-mentioned opacifying agent is titanium dioxide.

[0115] The preparation method of a vitamin K2 (MK-7) soft capsule that promotes blood calcium t...

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Abstract

The invention relates to the technical field of health-care food, in particular to a vitamin K2 (MK-7) soft capsule for promoting blood calcium to enter bones and a preparation method. The vitamin K2(MK-7) soft capsule comprises a capsule liquid and a capsule skin, wherein the capsule liquid is prepared from the following raw materials in parts by weight: 30 to 60 parts of vitamin K2, 440 to 530parts of vegetable oil and 0.1 to 0.2 part of an antioxidant; the capsule skin is prepared from the following raw materials in parts by weight: 150 to 220 parts of gelatin and hydroxypropyl methyl cellulose, 110 to 180 parts of purified water, 45 to 80 parts of a plasticizer and 1 to 6 parts of an opacifying agent; the vitamin K2 (MK-7) soft capsule is prepared from the capsule liquid and the capsule skin through a certain preparation method. The composition has high activity and high stability, and can promote blood calcium to enter bones.

Description

[0001] 1. Technical field: [0002] The invention relates to the technical field of health food, in particular to a vitamin K2 (MK-7) soft capsule for promoting blood calcium to enter bone and a preparation method thereof. [0003] 2. Background technology: [0004] my country has entered and has been in an aging society for a long time. With the acceleration of population aging, the incidence of osteoporosis is also increasing year by year. The latest data show that the number of osteoporosis patients in my country has reached 140 million, and there are more women than men. Among them, the incidence rate of osteoporosis over the age of 40 is 24.62%. [0005] Osteoporosis is often accompanied by complications such as joint pain, short stature, and fractures. Although most fractures do not directly lead to death, they are highly disabling, leading to a decline in the quality of life of the individual, and will also affect the family and society. Bring a burden. [0006] Early ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K31/122A61K47/38A61K47/44A61K47/22A61P19/10A23L33/15
CPCA23V2002/00A61K9/4816A61K9/4858A61K31/122A23L33/15A61P19/10A23V2200/306
Inventor 贺兰雪王春锋王欢
Owner SHAANXI HEMING HEALTH TECH
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