Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Eye-protecting combined patch and preparation method thereof

A patch and hydrogel patch technology, applied in the field of microneedles, can solve the problems of slow dissolution and absorption rate of water-soluble microneedles, slow dissolution and absorption of water-soluble components, and small amount of active ingredients loaded on microneedles, etc., to achieve good skin care Eye effect, eye fatigue relief, good degradability effect

Inactive Publication Date: 2020-04-03
广州新济薇娜生物科技有限公司
View PDF16 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, most of the microneedle products currently on the market use water-soluble soluble microneedles and use the microneedles alone to directly penetrate the stratum corneum of the skin. The slow rate of dissolution and absorption of sexual microneedles affects its use effect

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Eye-protecting combined patch and preparation method thereof
  • Eye-protecting combined patch and preparation method thereof
  • Eye-protecting combined patch and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] This embodiment provides an eye protection combination patch, which consists of a microneedle patch and a hydrogel patch.

[0056] Wherein, the microneedle patch is composed of a microneedle body and a microneedle base layer, and the microneedle body is prepared from the following raw materials in parts by weight:

[0057]

[0058]

[0059] The microneedle base layer is prepared from the following raw materials in parts by weight:

[0060] Sodium hyaluronate (molecular weight 28W) 5 parts

[0061] 15 parts of hydroxypropyl cellulose

[0062] 80 parts of water.

[0063] The preparation method of the above-mentioned microneedle patch is as follows:

[0064] (1) Dissolve lutein, sodium hyaluronate (molecular weight: 5000), polyvinylpyrrolidone K90, and mannitol in water to obtain a needle solution, and then inject the needle solution into a 100×100 PDMS female mold , place the entire mold in an environment of 0.5 MPa, pressurize for 5 minutes, pour the needle sol...

Embodiment 2

[0075] This embodiment provides an eye protection combination patch, which consists of a microneedle patch and a hydrogel patch.

[0076] Wherein, the microneedle patch is composed of a microneedle body and a microneedle base layer, and the microneedle body is prepared from the following raw materials in parts by weight:

[0077]

[0078]

[0079] The microneedle base layer is prepared from the following raw materials in parts by weight:

[0080] Sodium hyaluronate (molecular weight 28W) 5 parts

[0081] 15 parts of hydroxypropyl cellulose

[0082] 80 parts of water.

[0083] The preparation method of the above-mentioned microneedle patch is as follows:

[0084] (1) Dissolve lutein, retinyl acetate, sodium hyaluronate (molecular weight is 5000), polyvinylpyrrolidone K90, and mannitol in water to obtain a needle solution, and then inject the needle solution into 100 In the PDMS negative mold of ×100, place the entire mold in an environment of 0.5 MPa, pressurize for 5...

Embodiment 3

[0095] This embodiment provides an eye protection combination patch, which consists of a microneedle patch and a hydrogel patch.

[0096] Wherein, the microneedle patch is composed of a microneedle body and a microneedle base layer, and the microneedle body is prepared from the following raw materials in parts by weight:

[0097]

[0098]

[0099] The microneedle base layer is prepared from the following raw materials in parts by weight:

[0100] Sodium hyaluronate (molecular weight 28W) 5 parts

[0101] 15 parts of hydroxypropyl cellulose

[0102] 80 parts of water.

[0103] The preparation method of the above-mentioned microneedle patch is as follows:

[0104] (1) Dissolve lutein ester, retinyl acetate, sodium hyaluronate (molecular weight: 5000), polyvinylpyrrolidone, and mannitol in water to obtain a needle solution, and then inject the needle solution into 100 In the PDMS negative mold of ×100, place the entire mold in an environment of 0.5 MPa, pressurize for 5...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Molecular weightaaaaaaaaaa
Login to View More

Abstract

The invention relates to an eye-protecting combined patch and a preparation method thereof. The eye-protecting combined patch comprises a microneedle patch and a hydrogel patch, wherein the microneedle patch consists of a microneedle body and a microneedle substrate layer; the microneedle body is prepared from an active component and a microneedle auxiliary material; the active component is at least one of retinol acetate, lutein and lutein ester; the microneedle auxiliary material consists of a high polymer material and a water-soluble small molecular compound; the hydrogel patch is preparedby attaching hydrogel to a patch substrate; and the hydrogel is prepared from the following raw material components: glycerin, sodium polyacrylate, sodium hyaluronate, tartaric acid, aluminum glycinate, EDTA-2Na, lutein, retinol acetate and water. The eye-protecting combined patch has a good eye-protecting effect and can effectively improve the eyesight of a myopia patient.

Description

[0001] field of invention [0002] The invention belongs to the field of microneedles, and in particular relates to an eye protection combined patch and a preparation method thereof. Background technique [0003] Everyone hopes to have a pair of clear and bright eyes, but with the development of modern technology, the upgrading of electronic products and the changes in work and rest methods and work and rest time, whether it is children, adolescents, young adults or middle-aged and elderly people, the visual acuity All decreased significantly. [0004] On April 29, 2019, the National Health Commission held a regular press conference. At the meeting, the results of the 2018 survey on myopia among children and adolescents organized by the National Health Commission, the Ministry of Education and the Ministry of Finance were introduced. There were 69,200 kindergarten children (6 years old), and 1,049,200 primary and middle school students of all grades. The results of the surv...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61M37/00A61K9/00A61K9/70A61K47/26A61K47/32A61K47/36A61K47/38A61P27/02A61P27/10A61K31/22A61K31/047
CPCA61M37/0015A61K9/0021A61K9/70A61K9/0048A61K47/36A61K47/32A61K47/26A61K47/38A61P27/02A61P27/10A61K31/22A61K31/047A61M2037/0046A61M2037/0053A61K2300/00
Inventor 温新国张敏敏杨思超陈航平冯家颖任春艳
Owner 广州新济薇娜生物科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com