Composition of timolol or salt of timolol, hydrogel emplastrum of composition, and purpose for treating angioma

Abstract

The invention relates to a composition of timolol or a salt of the timolol, hydrogel emplastrum of the composition, and a purpose for treating angioma, in particular to timclol maleate hydrogel emplastrum used for treating infant angioma. The composition of the timolol or the salt of the timolol comprises a stabilizer to improve the light stability of a medicinal preparation of the timolol or thesalt of the timolol. The hydrogel emplastrum of the timolol or the salt of the timolol comprises the timolol or the salt of the timolol, particularly maleate, the stabilizer, a high-molecular polymer,a wetting agent, a cross-linking agent, a cross-linking conditioning agent, a pH value conditioning agent (appropriate amount is 2-8), a viscosity conditioning agent, a preservative, a filling agentand purified water. The composition and the preparation disclosed by the invention have good light stability, viscosity and a comfort level, and medicines slowly and smoothly release so as to prolongmedicine acting time. The hydrogel emplastrum can be repeatedly uncovered and pasted, does not irritate skin, is convenient in use, has a long-lasting effect, is high in stability, has a simple production technology, is suitable for industrial production and is free from "three wastes (industrial wastewater, waste gases and residues)".

Description

technical field [0001] The invention relates to the field of medicine, in particular to a timolol or a salt composition thereof for treating hemangiomas, in particular to a timolol maleate hydrogel plaster for treating infantile hemangiomas. Background technique [0002] Infantile hemangioma is a benign tumor originating from blood vessels in the skin. It appears when the baby is born or within 3-6 months after birth. It often occurs on the head, face and neck. It usually grows rapidly in 2-8 months, affecting the appearance of the baby. In addition, dangerous infantile hemangiomas, such as those growing in the eyes, throat, and extremities, need special attention and need timely treatment. Its clinical incidence rate is about 4%-10%, and there is an increasing trend every year. Hemangioma has its own law of growth and regression, but during the whole growth cycle of hemangioma, symptoms such as bleeding, erosion, affecting appearance, and even affecting the function of imp...

AI Technical Summary

Problems solved by technology

The effect of radiation therapy is not sure yet, and it may cause cancer, so it is rarely used at present

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