Traditional Chinese medicine composition for treating osteoarthritis and preparation method and application of traditional Chinese medicine composition

Abstract

The invention discloses a traditional Chinese medicine composition for treating osteoarthritis and a preparation method and application of the traditional Chinese medicine composition. The compositionhas the effects of removing cold and dampness, relaxing muscles and stasis, dissipating and relieving pain and nourishing liver and kidney. The traditional Chinese medicine composition is prepared from the raw material components: in parts by weight, 75-100 parts of Rehmannia glutinosa, 5-50 parts of fructus psoraleae, 5-50 parts of deer-horn glue, 5-45 parts of radix achyranthis bidentatae, 5-35parts of Semen Cuscutae, 5-35 parts of baked ginger, 5-15 parts of ephedra, 5-35 parts of cinnamon, 5-35 parts of Semen brassicae, 5-35 parts of rhizoma bletillae, 5-25 parts of corydalis tuber and 5-25 parts of licorice. It is clinically proven that the traditional Chinese medicine composition is suitable for knee osteoarthritis with the main clinical signs of wind-evil and dampness pain syndromes and cold-damp stagnation syndromes, and the clinical symptoms of patients with knee osteoarthritis can be improved. It is shown through pharmacodynamics study that the traditional Chinese medicinecomposition is capable of improving the symptoms and related indicators of papain-induced osteoarthritis of rats, is suitable for patients with knee osteoarthritis with the wind-evil and dampness painsyndromes and cold-damp stagnation syndromes, and has a high clinical application value.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and specifically relates to a traditional Chinese medicine composition, a traditional Chinese medicine composition for treating osteoarthritis, and a preparation method and application thereof. Background technique [0002] Osteoarthritis (OA) is also called degenerative arthritis, proliferative arthritis, hypertrophic arthritis, etc., but they all refer to the same type of arthritis. In recent years, they are generally collectively referred to as "osteoarthritis". According to the classification of the American Rheumatism Association, OA is divided into primary OA and secondary OA. The exact cause of the former is unclear, and may include age, gender, occupation, race, obesity, genetics, and excessive exercise; the latter is secondary to any joint injury or disease, such as meniscus injury, intra- or peri-articular fractures, and joint ligament injuries , Congenital malformation...

AI Technical Summary

Problems solved by technology

However, due to the unclear etiology and pathogenesis, both Chinese and Western medicine have not achieved the desired therapeutic effect on this disease.

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