Traditional Chinese medicine composition for treating osteoarthritis and preparation method and application of traditional Chinese medicine composition

A technology of osteoarthritis and composition, applied in the field of traditional Chinese medicine, can solve the problems of not achieving ideal therapeutic effect, unclear pathogenesis, etc.

Inactive Publication Date: 2020-04-28
JILIN ACAD OF TRADITIONAL CHINESE MEDICINE
View PDF1 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the unclear etiology and pathogenesis, both Chinese and Western medicine have not achieved the desired therapeutic effect on this disease.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine composition for treating osteoarthritis and preparation method and application of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating osteoarthritis and preparation method and application of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating osteoarthritis and preparation method and application of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0023] The clinical efficacy of the present invention is observed as follows:

[0024] Western medicine diagnosis: knee osteoarthritis (ICD-10 code: M19.966). The diagnosis was confirmed according to the "Guidelines for the Diagnosis and Treatment of Knee OA in Osteoarthritis 2007" formulated by the Orthopedic Branch of the Chinese Medical Association.

[0025] Diagnostic criteria:

[0026] 1. Repeated knee joint pain in the past 1 month;

[0027] 2. Standing or weight-bearing position X-ray film shows narrowing of the joint space, subchondral bone sclerosis; and (or) cystic degeneration, joint margin osteophyte formation; 3. Synovial fluid is clear and viscous at least twice, WBC <2000 pcs / ml;

[0028] 4. Middle-aged and elderly patients ≥40 years old;

[0029] 5. Morning stiffness ≤ 30 minutes;

[0030] 6. There is a sense of bone friction during activities.

[0031] Note: Comprehensive clinical, laboratory and X-ray examinations, in line with 1+2 or 1+3+5+6 or 1+4+5+6, can diagnose kne...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a traditional Chinese medicine composition for treating osteoarthritis and a preparation method and application of the traditional Chinese medicine composition. The compositionhas the effects of removing cold and dampness, relaxing muscles and stasis, dissipating and relieving pain and nourishing liver and kidney. The traditional Chinese medicine composition is prepared from the raw material components: in parts by weight, 75-100 parts of Rehmannia glutinosa, 5-50 parts of fructus psoraleae, 5-50 parts of deer-horn glue, 5-45 parts of radix achyranthis bidentatae, 5-35parts of Semen Cuscutae, 5-35 parts of baked ginger, 5-15 parts of ephedra, 5-35 parts of cinnamon, 5-35 parts of Semen brassicae, 5-35 parts of rhizoma bletillae, 5-25 parts of corydalis tuber and 5-25 parts of licorice. It is clinically proven that the traditional Chinese medicine composition is suitable for knee osteoarthritis with the main clinical signs of wind-evil and dampness pain syndromes and cold-damp stagnation syndromes, and the clinical symptoms of patients with knee osteoarthritis can be improved. It is shown through pharmacodynamics study that the traditional Chinese medicinecomposition is capable of improving the symptoms and related indicators of papain-induced osteoarthritis of rats, is suitable for patients with knee osteoarthritis with the wind-evil and dampness painsyndromes and cold-damp stagnation syndromes, and has a high clinical application value.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and specifically relates to a traditional Chinese medicine composition, a traditional Chinese medicine composition for treating osteoarthritis, and a preparation method and application thereof. Background technique [0002] Osteoarthritis (OA) is also called degenerative arthritis, proliferative arthritis, hypertrophic arthritis, etc., but they all refer to the same type of arthritis. In recent years, they are generally collectively referred to as "osteoarthritis". According to the classification of the American Rheumatism Association, OA is divided into primary OA and secondary OA. The exact cause of the former is unclear, and may include age, gender, occupation, race, obesity, genetics, and excessive exercise; the latter is secondary to any joint injury or disease, such as meniscus injury, intra- or peri-articular fractures, and joint ligament injuries , Congenital malformation...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P19/02A61P19/08A61P29/00A61K35/32
CPCA61K35/32A61K36/17A61K36/21A61K36/31A61K36/39A61K36/43A61K36/484A61K36/487A61K36/54A61K36/66A61K36/804A61K36/898A61K36/9068A61K2236/331A61K2236/39A61P19/02A61P19/08A61P29/00A61K2300/00
Inventor 洪铁吴岩
Owner JILIN ACAD OF TRADITIONAL CHINESE MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap