Aerosol supply and regulation system and application thereof in evaluation of electronic cigarette liquid inhalation exposure safety

Abstract

The invention discloses an aerosol supply and regulation system. The aerosol supply and regulation system comprises a peristaltic infusion pump, a thermal aerosol generator, a main controller and a diluent gas flowmeter. A gas inlet of the thermal aerosol generator is connected with the diluent gas flowmeter through an aerosol diluent gas pipeline, and the amount of diluent gas entering the thermal aerosol generator can be adjusted. A liquid inlet of the thermal aerosol generator is connected with the peristaltic infusion pump through an electronic cigarette liquid conveying pipe. The main controller is electrically connected with the peristaltic infusion pump and a heating module in the thermal aerosol generator and controls starting, stopping and the transmission rate of the peristalticinfusion pump and the heating temperature of the heating module. The invention also discloses an application of the system in evaluation of electronic cigarette liquid inhalation exposure safety. Theaerosol supply and regulation system provided by the invention can meet the requirements of electronic cigarette liquid inhalation exposure safety evaluation, provides aerosol required by safety evaluation, is low in cost and stable and reliable in performance, and can be popularized on a large scale.

Description

technical field [0001] The invention relates to the technical field of electronic cigarette safety evaluation, in particular to an aerosol supply and regulation system and its application in the safety evaluation of electronic cigarette liquid inhalation exposure. Background technique [0002] Electronic cigarettes (e-cigarettes), also known as electronic nicotine delivery systems (ENDS), are a new form of nicotine intake that looks similar to cigarettes. Electronic cigarettes are mainly composed of three parts: pods, atomizers and batteries. The atomizer is powered by a battery rod, which can convert the liquid nicotine in the pod into mist, so that the user has a smoking-like feeling when inhaling. E-cigarette liquid is a liquid used in electronic cigarette pods. The main ingredients include propylene glycol, glycerin, nicotine, various additives, etc. The principle of e-cigarettes is that the e-cigarette liquid passes through a heated coil to form a vapor state, and af...

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Problems solved by technology

[0004] E-cigarette liquid inhalation exposure safety evaluation studies usually use expensive smoking machines to smoke e-cigarettes. According to a certain smoking mode, through a battery power device, the nebulizer heats up and atomizes the e-liquid to form an aerosol, and the cigarette needs to be replaced. bomb, and the aerosol concentration that can be achieved is very limited

If you don’t use a smoking machine, you can also use a liquid aerosol generator. The liquid aerosol generators commonly used in the market are based on the principle of ultrasonic atomization and high-pressure atomization, which is completely different from the principle of electric heating atomization of electronic cigarettes. , and the atomized aerosol concentration is low, and the concentration is single

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