Antibacterial polyurethane slow rebound foam and preparation method thereof
A technology of slow rebound and polyurethane, which is applied in the field of polyurethane material preparation, can solve the problems that the antibacterial and antifungal properties have not been greatly improved, and the antibacterial and antifungal properties have not been greatly improved, etc. Effects of degrading biological activity, enhancing antibacterial activity, and improving solubility
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[0033] see figure 1Shown, the invention provides a kind of preparation method of antibacterial polyurethane slow resilience foam, comprises the steps:
[0034] S1. Preparation of quaternary ammonium salt-modified chitosan: weigh a predetermined amount of chitosan, add 40% sodium hydroxide aqueous solution and isopropanol, stir and heat to 50-60°C for 1-3 hours of alkalization Then dropwise add 3-chloro-2-hydroxypropyltrimethylammonium chloride solution with a concentration of 35%, raise the temperature to 70-80°C for 8-10 hours, filter, wash and dry to obtain the quaternary ammonium salt Modified chitosan;
[0035] S2. Preparation of guanidinium-modified chitosan: configure a predetermined amount of 0.5mol / L hydrochloric acid solution, slowly add a predetermined amount of chitosan, stir for 40-60 minutes, then add absolute ethanol for precipitation, stir, suction filter and dry. Chitosan hydrochloride is obtained; the chitosan hydrochloride is added to deionized water and mi...
Embodiment 1
[0046] The preparation method of antibacterial polyurethane slow rebound foam:
[0047] S1. Preparation of quaternary ammonium salt modified chitosan: Weigh 5g of chitosan, add 50mL of 40% sodium hydroxide aqueous solution and 150mL of isopropanol, heat to 50°C under stirring and basify at constant temperature for 2h; slowly drop 25g 3-chloro-2-hydroxypropyltrimethylammonium chloride solution with a concentration of 35%, then heated up to 75°C, kept at a constant temperature for 9 hours, adjusted the pH to ≤7 with dilute hydrochloric acid after the reaction, filtered, washed and dried to obtain quaternary Ammonium salt modified chitosan.
[0048] S2. Preparation of guanidine-modified chitosan: configure 100 mL of 0.5 mol / L hydrochloric acid solution, then slowly add 5.0 g of chitosan, stir with a magnetic stirrer for 40 min, then add 3 times the volume of absolute ethanol for precipitation, and stir Suction filter and dry after uniformity to obtain chitosan hydrochloride; wei...
Embodiment 2-5
[0060] The difference with Example 1: in the preparation process of step S3, the massfraction of guanidino-modified chitosan and quaternary ammonium salt modified chitosan are different, other steps are all the same as Example 1, no longer repeat.
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