Automatic pipetting system and control method thereof

Abstract

The invention discloses an automatic pipetting system, which comprises a cell culture box, a liquid preparation and pipetting operation device and an automatic gun head arrangement device, and is characterized in that the cell culture box is internally provided with a hollow cylindrical upper and lower multi-layer annular platform component for placing a cell culture plate; a rotary robot is arranged at the hollow position of the cylinder and is used for taking and conveying the cell culture plate by moving up and down and rotating in a horizontal plane; the automatic gun head arranging devicearranges disordered gun heads into a gun head array through vibration and steric hindrance. The liquid preparation and pipetting operation device comprises a pipetting gun or a pipetting gun array, and is used for loading and unloading the gun head array arranged by the automatic gun head arrangement device and performing liquid suction operation or liquid adding operation on the cell culture plate conveyed from the cell culture box on the pipetting operation platform. According to the invention, automatic cell inoculation, culture solution replacement, regulation factor or lead compound addition, automatic storage of the cell culture plate and the like can be carried out.

Description

technical field [0001] The invention relates to the technical field of life sciences, in particular to an automatic pipetting system for cell culture and a control method thereof. Background technique [0002] Cell-based gene function research and drug lead compound screening are two important links in the life science basic research and drug development process. It is necessary to add different concentrations of regulatory factors or small molecular compounds to the cell culture medium, and then affect the physiological function of the cells. Status and functionality are checked. The above studies all involve large-scale culture of cells, adding different concentrations of small molecule compounds to the cultured cells, and detecting the effects of the added compounds on the cells. Under the current circumstances, most laboratories at home and abroad mainly rely on small equipment, such as pipettes, electrophoresis instruments, centrifuges, PCR instruments, etc. to complet...

AI Technical Summary

Problems solved by technology

[0004] Although many lead compound screenings at the level of pharmaceutical companies such as pharmaceutical companies rely on mechanical operations, the instruments used are either for automated cell culture or for detection of cultured cells. There is no equipment that can be fully automated on microplates. High-throughput cell culture, medium replacement, and addition of different compounds to different culture wells for functional testing and other operations

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