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A kind of antifungal composition, its external preparation and application

A technology of external preparations and compositions, applied in the field of medicine, to achieve the effect of treating fungal infectious diseases

Active Publication Date: 2021-02-19
ZHONGSHAN WANHAN PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Since the monomer structure of polyvinyl alcohol is relatively simple, modification of the free hydroxyl groups (such as acylation, etc.) may change its spatial structure, thereby affecting its interaction with povidone-iodine spatial structure to produce synergy. Antibacterial effect, there is no technical inspiration in the prior art that any structural modification can produce the above effect

Method used

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  • A kind of antifungal composition, its external preparation and application
  • A kind of antifungal composition, its external preparation and application
  • A kind of antifungal composition, its external preparation and application

Examples

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Embodiment Construction

[0024] In order to make the technical means, creative features, goals and effects achieved by the present invention easy to understand, the following specific examples are used to further illustrate the present invention, but the following examples are only preferred embodiments of the present invention, not all. Based on the examples in the implementation manners, other examples obtained by those skilled in the art without making creative efforts all belong to the protection scope of the present invention.

[0025] In the following examples, unless otherwise specified, the operating methods used are conventional operating methods, and the equipment used is conventional equipment.

[0026] Unless otherwise specified, the units of all parameters related to concentration in the present invention are μg / L.

[0027] In the following examples, the mass ratio of povidone iodine and polyvinyl acetate is represented by a single number, and ":1" is omitted. For example, the mass ratio ...

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Abstract

The invention discloses an antifungal composition as well as an external preparation and application thereof, and relates to the technical field of medicines. The composition is prepared from povidoneiodine and polyvinyl alcohol acetate. The pharmaceutical preparation is an external preparation, wherein the composition and the pharmaceutical preparation can be used for preparing medicines for treating fungal infectious diseases. Povidone iodine and polyvinyl alcohol acetate in the composition disclosed by the invention can generate an excellent synergistic bacteriostatic effect on various pathogenic fungi; so that the external preparation prepared from the composition can be used for effectively treating fungal infectious diseases such as fungal vaginitis.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to an antifungal composition, its external preparation and its application. Background technique [0002] Povidone-iodine (Polyvinyl pyrrolidone-Iodine, PVP-I), also known as iodophor, is the only iodine-containing disinfection preparation recorded in the Chinese Pharmacopoeia, and has become an internationally recognized high-efficiency, broad-spectrum, non-toxic fungicide. It has strong bactericidal power and broad bactericidal spectrum, and has a strong and rapid killing effect on gram-positive bacteria, gram-negative bacteria, viruses, spores, fungi, protozoa, etc. The disinfection of its environment has important application value in medicine and daily chemicals. [0003] Povidone-iodine is formed by complexing the polymer-polyvinylpyrrolidone (PVP) with iodine as the carrier. Polyvinylpyrrolidone is a non-ionic surfactant, which has no antibacterial effect itself and forms w...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K47/32
CPCA61K9/0014A61K9/0031A61K9/0034A61K9/02A61K9/06A61K33/18A61K47/32A61P15/02A61P31/10
Inventor 向飞杜志博吴彦勍彭韪
Owner ZHONGSHAN WANHAN PHARM CO LTD
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