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A combined antibacterial substance containing water extract of pomegranate peel and water extract of Zanthoxylum bungeanum

The technology of water extract and prickly ash seeds is applied in the field of preparation of water extracts of pomegranate peel and prickly ash seeds and the application field of antibacterial combination. rate effect

Active Publication Date: 2022-01-25
CHANGZHOU MYSUN BIOLOGICAL MATERIALS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is difficult to further improve the antibacterial effect

Method used

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  • A combined antibacterial substance containing water extract of pomegranate peel and water extract of Zanthoxylum bungeanum
  • A combined antibacterial substance containing water extract of pomegranate peel and water extract of Zanthoxylum bungeanum
  • A combined antibacterial substance containing water extract of pomegranate peel and water extract of Zanthoxylum bungeanum

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0030] A pomegranate skin extract, including the following steps

[0031] (1) Crush the pomegranate skin, over 80 mesh sieve to get the pomegranate skin;

[0032] (2) Place 100g of pomegranate rude powder in the flask, and the heat generator is a heating device, and the coarse powder is 6-fold mass distilled water, and the heat reflow is heat-refluxed at 90 ° C for 60 minutes by heat generation. After filtration, the filtrate is added. Equisical for 60 minutes, then filtrate the filtrate, then centrifuate at the centrifuge 9000r / min twice, and taking the upper clarified liquid;

[0033] (3) Clarify extract with porcelain crucible to concentrate 10% of the original volume in the water bath 90 ° C;

[0034] (4) Transfer the concentrate to the container, put it in -80 ° C freezer for 1 hour, and then dry in the vacuum freeze dryer, temperature conditions - 40 ° C, drying under the pressure condition 11Pa, grind, sealed .

experiment example 2

[0036] A pepper seed water extract, including the following steps

[0037] (1) Crush the pepper seeds, 80 mesh sieve to the pepper seed coarse powder;

[0038] (2) Place 100g pepper seed rough powder in the flask, the electric heater is a heating device, the coarse powder 6 times the mass distilled water is added, and the heat reflow method is added to 90 ° C for 60 minutes at 90 ° C, and then add the filtration. Equal mass distilled water solvent was extracted for 60 minutes, then filtered filtrate, and the filtrate was centrifuged at 9000 r / min of the centrifuge for 5 minutes, and the upper clarified liquid was taken;

[0039] (3) Clarify extract with porcelain crucible to concentrate 10% of the original volume in the water bath 90 ° C;

[0040] (4) Transfer the concentrate to the container, put it in -80 ° C freezer for 1 hour, and then dry in the vacuum freeze dryer, temperature conditions - 40 ° C, drying under the pressure condition 11Pa, grind, sealed .

[0041] Experimen...

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PUM

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Abstract

The invention provides a combined bacteriostatic compound containing water extract of pomegranate peel and water extract of Zanthoxylum bungeanum seed, which belongs to the technical field of bacteriostatic agents. The water extract of pomegranate peel and Zanthoxylum bungeanum seed is obtained by heat reflux method, and the filtrate is freeze-dried to obtain that, wherein the yield of water extract of pomegranate peel and Zanthoxylum bungeanum seed is 20-25%. %. The mass ratio of the pomegranate peel and the Zanthoxylum bungeanum water extract in the combined antibacterial substance containing the water extract of pomegranate peel and the water extract of Zanthoxylum bungeanum seed is 1:1. The above-mentioned combined bacteriostatic substance containing the water extract of pomegranate peel and the water extract of Zanthoxylum bungeanum seed has good synergistic antibacterial effect on Staphylococcus aureus, and the minimum 3.125mg / mL can achieve the antibacterial effect.

Description

Technical field [0001] The present invention belongs to the field of antibacterial agents, and specific to the preparation of pomegranate skin and pepper seed watermarks and antibacterial combinations. Background technique [0002] With the improvement of modernization, whether it is production or the spread of bacteria in life, bacterial fungi causes some or large public health safety issues, which cannot be underestimated. [0003] At present, the inhibitory agents in the world can be divided into organic antibiotics, inorganic antibacterial agents, organic and inorganic antibacterial injuries, which is prone to environmental pollution, natural antibacterial agents are also plant source The antibacterial agent, animal source infestacter and microbial bacteria, plant source infestogenesis is wide, non-toxic and non-polluting. [0004] Pomegranate skin (learning name: Grenadine pericarpium) is a dry peel (learning name: Punicagranatum L.), according to the "Chinese Pharmacopoeia"...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/758A61P31/04A01N65/36A01N65/08A01P1/00A01P3/00A61K8/9789A61Q17/00A23L3/3472
CPCA61K36/758A61K36/185A61P31/04A01N65/36A01N65/08A01N65/00A61K8/9789A61Q17/005A23L3/3472A61K2236/331A61K2236/39A23V2002/00A61K2300/00A23V2200/10A23V2250/21A23V2300/14A23V2300/20A23V2300/38
Inventor 欧佳存纪俊玲汪媛陈海群何光裕陈群夏晗谈君婕
Owner CHANGZHOU MYSUN BIOLOGICAL MATERIALS
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